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Which of the following is an example of a mutual prodrug?(a) Prontosil is the prodrug for sulfanamide(b) Aspirin is the prodrug of salicylic acid(c) Benorylate prodrug for NSAIDs and paracetamol(d) Diesters pro-prodrug for pilocarpic acidThe question was asked in class test.Origin of the question is Prodrugs in section Prodrugs & Excretion of Drugs of Drug Biotechnology

Answer»

The correct answer is (c) Benorylate prodrug for NSAIDs and paracetamol

For explanation: Mutual prodrug is pro-drugs COMPRISING of 2 pharmacologically active AGENTS COUPLED together to form a single product. Thus, benorylate prodrug for NSAIDs and paracetamol is an EXAMPLE of mutual prodrug.



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