Which of the following is not a disadvantage of site-specific drug delivery?(a) May lead to toxic effects on other non-target tissues(b) May get diluted(c) Less distribution time(d) No penetrable to the target tissueThe question was asked in unit test.My query is from Prodrugs in portion Prodrugs & Excretion of Drugs of Drug Biotechnology

Which of the following is not a disadvantage of site-specific drug del

1.	Which of the following is not a disadvantage of site-specific drug delivery?(a) May lead to toxic effects on other non-target tissues(b) May get diluted(c) Less distribution time(d) No penetrable to the target tissueThe question was asked in unit test.My query is from Prodrugs in portion Prodrugs & Excretion of Drugs of Drug Biotechnology
Answer» Right choice is (c) Less DISTRIBUTION TIME To explain I would say: Less distribution time is an advantage for the drug. The disadvantages are may lead to toxic effects to other non-TARGET TISSUES, may get diluted due to distribution and smaller fraction reach the target tissue, May not be able to penetrate the target tissue, higher distribution time.

Discussion

No Comment Found

Related InterviewSolutions

Which drugs cannot be filtered through glomerulus?(a) Drugs bound to plasma proteins(b) Unbound(c) Free drug(d) Below molecular weight of 300 DaltonThis question was posed to me during an online interview.This interesting question is from Drugs Excretion in division Prodrugs & Excretion of Drugs of Drug Biotechnology
In a graph of renal clearance versus plasma drug concentration, which kind of drug will give the below shown curve?(a) Drug excreted only by filtration(b) Drug filtered and actively reabsorbed(c) Drug filtered as well as actively secreted(d) Drug reabsorbed activelyThis question was addressed to me in an interview for internship.My question is from Drugs Excretion in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
Drugs of molecular range 300-500 Dalton will be excreted out by glomerulus.(a) True(b) FalseThis question was posed to me in an international level competition.Enquiry is from Drugs Excretion topic in portion Prodrugs & Excretion of Drugs of Drug Biotechnology
What is the equation for clearance?(a) Elimination rate / plasma drug concentration(b) Plasma drug concentration/elimination rate(c) 1 / Plasma drug concentration(d) 1 / Elimination rateThis question was posed to me during an interview.My query is from Drugs Excretion topic in section Prodrugs & Excretion of Drugs of Drug Biotechnology
In the following diagram which organ name should be in the place of ‘?’?(a) Small intestine(b) Large intestine(c) Liver(d) KidneyThis question was addressed to me in an interview for job.This intriguing question comes from Drugs Excretion in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
Which of the following will not be a limitation for prodrug design?(a) Formation of toxic product(b) An inert carrier can be cleaved off forming toxic product(c) Product cleaving off before reaching the target site(d) The cleaving of the carrier is also site-specificI had been asked this question during an interview for a job.I'm obligated to ask this question of Prodrugs topic in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
In a graph of rate of excretion versus plasma drug concentration, which kind of drug will give the below shown curve?(a) Drug excreted only by filtration(b) Drug filtered and actively reabsorbed(c) Drug filtered as well as actively secreted(d) Drug reabsorbed activelyThe question was posed to me in an online quiz.My doubt stems from Drugs Excretion topic in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
Which of the following is not a physicochemical factor of drug that can affect the renal excretion?(a) Molecular size(b) Disintegration rate(c) pKa of the drug(d) Lipid solubilityThe question was asked in an online quiz.Question is taken from Drugs Excretion topic in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
The rate of urine flow influences the extent of reabsorption.(a) True(b) FalseI have been asked this question during an interview.My query is from Drugs Excretion in chapter Prodrugs & Excretion of Drugs of Drug Biotechnology
Which of the following is not a factor influencing pulmonary excretion?(a) Pulmonary blood flow(b) The solubility of volatile substance(c) Rate of respiration(d) Heart rateThis question was addressed to me in a national level competition.This question is from Drugs Excretion in section Prodrugs & Excretion of Drugs of Drug Biotechnology

Discussion

No Comment Found

Related InterviewSolutions

Reply to Comment