Which of the following is not true about the guard column used in liquid chromatography?(a) It filters particles that clog the separation column(b) It extends the lifetime of separation column(c) It allows particles that cause precipitation upon contact with stationary or mobile phase(d) The size of packing varies with the type of protection neededThis question was addressed to me in a job interview.Asked question is from Liquid Chromatography topic in portion Chromatography of Analytical Instrumentation

Which of the following is not true about the guard column used in liqu

1.	Which of the following is not true about the guard column used in liquid chromatography?(a) It filters particles that clog the separation column(b) It extends the lifetime of separation column(c) It allows particles that cause precipitation upon contact with stationary or mobile phase(d) The size of packing varies with the type of protection neededThis question was addressed to me in a job interview.Asked question is from Liquid Chromatography topic in portion Chromatography of Analytical Instrumentation
Answer» The correct answer is (c) It allows particles that cause precipitation upon CONTACT with stationary or mobile phase To explain I would SAY: GUARD column removes particles that cause precipitation upon contact with stationary or mobile phase. It is PLACED before the separation column.

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