Which of the following is not true regarding the BLOCKS?(a) The BLOCKS server can extract a conserved, ungapped region from a MSA to produce a sequence block(b) The server can also find blocks in a set of unaligned, input sequences and maintains a large database of blocks based on an analysis of proteins in the Prosite catalog(c) Blocks are found by the Protomat program(d) The program MOTIF doesn’t locate spaced patternsI got this question during an online exam.This key question is from Localized Alignments in Sequences topic in portion Multiple Sequence Alignment of Bioinformatics

Which of the following is not true regarding the BLOCKS?(a) The BLOCKS

1.	Which of the following is not true regarding the BLOCKS?(a) The BLOCKS server can extract a conserved, ungapped region from a MSA to produce a sequence block(b) The server can also find blocks in a set of unaligned, input sequences and maintains a large database of blocks based on an analysis of proteins in the Prosite catalog(c) Blocks are found by the Protomat program(d) The program MOTIF doesn’t locate spaced patternsI got this question during an online exam.This key question is from Localized Alignments in Sequences topic in portion Multiple Sequence Alignment of Bioinformatics
Answer» Right answer is (d) The PROGRAM MOTIF doesn’t locate spaced patterns Easiest explanation: Blocks are found in two steps: FIRST, the program MOTIF described on the previous page is USED to locate spaced patterns. The SECOND step takes the best and most consistent patterns found in step 1 and uses the program MOTOMAT to merge overlapping triplets and extend them, orders the resulting blocks, and chooses those that are in the largest subset of sequences.

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