Which of the following is the first antihistamine?(a) Piperoxan(b) Ethylenediamine(c) Alkylamines(d) TricyclicsThe question was asked during an internship interview.The question is from Drug Concentration and Pharmacologic Response topic in division Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology

Which of the following is the first antihistamine?(a) Piperoxan(b) Eth

1.	Which of the following is the first antihistamine?(a) Piperoxan(b) Ethylenediamine(c) Alkylamines(d) TricyclicsThe question was asked during an internship interview.The question is from Drug Concentration and Pharmacologic Response topic in division Applications of Pharmacokinetic Principles, Diuretics, Drug Concentration and Pharmacologic Response of Drug Biotechnology
Answer» Right answer is (a) Piperoxan To ELABORATE: Piperoxan is discovered in 1933 by Jeff Forneau and Daniel Bovent while DEVELOPING a GUINEA pig animal model of anaphylaxis. They RECEIVED the Nobel Prize in 1957. Classes of first-generation H1 receptor antagonist antihistamines are ethylenediamines, ethanolamines, alkylamines, piperazines, TRICYCLICS.

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