1.

Which of the following is untrue regarding the STRING?(a) Search Tool for the Retrieval of Interacting Genes/Proteins(b) Functional associations include only the direct protein-protein interactions(c) It is based on combined evidence of gene linkage, gene fusion and phylogenetic profiles(d) It is a web server that predicts gene and protein functional associationsThe question was posed to me in semester exam.Origin of the question is Protein Interactions in portion Functional Genomics & Proteomics of Bioinformatics

Answer»

The correct answer is (B) Functional associations INCLUDE only the direct protein-protein interactions

For explanation: Functional associations include both direct and indirect protein-protein interactions.

Indirect interactions can MEAN enzymes in the same PATHWAY sharing a common substrate or proteins REGULATING each other in the genetic pathway.



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