Which of the given statements is incorrect about Searching for orthologs to a protein family in an EST database?(a) Searches of EST databases for matches to a query sequence routinely produce minimal amounts of output that must be searched manually for significant hits(b) ESTs with a high percent identity with the query sequence, a long alignment with the query sequence, and a very low E value of the alignment score represent groups of paralogous and orthologous genes(c) To identify orthologs as the most closely related sequence, ESTs were aligned using the amino acid alignment as a guide(d) To identify orthologs as the most closely related sequence, a phylogenetic tree was produced by the maximum likelihood methodThe question was asked in examination.The origin of the question is Comparative Genomics topic in section Collecting & Storing Sequences in Laboratory of Bioinformatics