1.

Which one is the correct sequence for drug absorption through the oral route?(a) Absorption – Dissolution – Disintegration – Deaggregation(b) Disintegration – Dissolution – Deaggregation – Absorption(c) Disintegration – Deaggregation – Dissolution – Absorption(d) Disintegration – Deaggregation – Absorption – DissolutionThis question was addressed to me during an interview.This question is from Drug Absorption in portion Absorption of Drugs of Drug Biotechnology

Answer»

The CORRECT ANSWER is (c) Disintegration – Deaggregation – Dissolution – Absorption

For explanation: Disintegration of the drug and then Deaggregation and subsequent release of a drug. FOLLOWED by the dissolution of the drug in aqueous FLUIDS at the absorption site and the movement of the dissolved drug through the gastrointestinal membrane into the systemic CIRCULATION.



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