Which one of these is not a mechanism of the working of surfactants?(a) Promote wetting by increasing the effective surface area(b) Helps in the dissolution of drug(c) Better membrane contact of the drug(d) Decrease membrane permeabilityThe question was asked at a job interview.My query is from Dosage Form Factors Affecting Drug Absorption in chapter Absorption of Drugs of Drug Biotechnology

Which one of these is not a mechanism of the working of surfactants?(a

1.	Which one of these is not a mechanism of the working of surfactants?(a) Promote wetting by increasing the effective surface area(b) Helps in the dissolution of drug(c) Better membrane contact of the drug(d) Decrease membrane permeabilityThe question was asked at a job interview.My query is from Dosage Form Factors Affecting Drug Absorption in chapter Absorption of Drugs of Drug Biotechnology
Answer» Correct choice is (d) Decrease membrane PERMEABILITY Easiest explanation: Mechanism involved in the increased absorption of the drug is, promotion of WETTING through the increased SURFACE AREA. These also HELP in better membrane contact and enhanced membrane permeability.

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