Which one of these is not an example of a basic drug with pKa range 5-11?(a) Cromolyn(b) Imipramine(c) Amitriptyline(d) ChloroquineI have been asked this question during an interview.Origin of the question is Drugs Absorption topic in division Absorption of Drugs of Drug Biotechnology

Which one of these is not an example of a basic drug with pKa range 5-

1.	Which one of these is not an example of a basic drug with pKa range 5-11?(a) Cromolyn(b) Imipramine(c) Amitriptyline(d) ChloroquineI have been asked this question during an interview.Origin of the question is Drugs Absorption topic in division Absorption of Drugs of Drug Biotechnology
Answer» The correct choice is (a) Cromolyn To ELABORATE: Cromolyn pKa is 2.5. Rest all the other drugs are bases of Pka range 5-11.These are morphine analogues. Such drugs are BETTER absorbed from relatively ALKALINE conditions of the intestine where these molecules LARGELY exist in unionized form.

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Which one of these is not an example of a basic drug with pKa range 5-11?(a) Cromolyn(b) Imipramine(c) Amitriptyline(d) ChloroquineI have been asked this question during an interview.Origin of the question is Drugs Absorption topic in division Absorption of Drugs of Drug Biotechnology

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