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Which types of drugs get absorbed by ion-pair transport?(a) High lipophilicity(b) Oily droplets(c) Affinity for carriers(d) Drugs that ionize at all pH conditionsThe question was posed to me in an interview for job.My question is from Mechanisms of Drug Absorption topic in chapter Absorption of Drugs of Drug Biotechnology

Answer»

The CORRECT answer is (d) Drugs that ionize at all pH CONDITIONS

Explanation: Ion-Pair Transport is the mechanism where absorption of drugs like quaternary ammonium compounds, sulphonic acids get absorbed. These drugs can get ionize at all pH conditions. These neutral COMPLEXES have LIPOPHILICITY and AQUEOUS solubility for passive diffusion.



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