1.

WU-BLAST produces P scores and BLAST (NCBI) produces E scores where _________(a) E = ln (1 + P^2)(b) E = ln (1 – P^2)(c) E = ln (1 + P)(d) E = ln (1 – P)I got this question in an interview.The query is from Sequence Assembly and Gene Identification in portion Collecting & Storing Sequences in Laboratory of Bioinformatics

Answer»

The correct option is (d) E = ln (1 – P)

Best EXPLANATION: For values less than 0.05, E = P. The choice of a < 10-20 SCORE is a conservative one for IDENTIFICATION of orthologs that should have a similar DOMAIN structure.



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