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151.

In the following questions a statement of assertion followed by a statement of reason is given. Choose the correct answer out of the following choices.(i) Both assertion and reason are wrong.(ii) Both assertion and reason are correct statements but reason is not correct explanation of assertion.(iii) Assertion is correct statement but reason is wrong statement.(iv) Both assertion and reason are correct statements and reason is correct explanation of assertion.(v) Assertion is wrong statement but reason is correct statement.Assertion : Acylation of amines gives a monosubstituted product whereas alkylation of amines gives polysubstituted product.Reason : Acyl group sterically hinders the approach of further acyl groups.

Answer»

(iii) Assertion is correct statement but reason is wrong statement.

152.

Write IUPAC name of the following compound: (CH3)2 N-CH2CH3

Answer»

N, N -Dimethylethylamine

153.

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Answer»

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154.

Arrange the following compounds in the decreasing order of their basic nature in the gaseous phase :Ammonia, N-methylhexanamine, propan-1- amine and N, N-dimethylethanolamine.

Answer»

Propan-1-amine < N-methylethanamine < N,N-dimethylmethanamine < ammonia

155.

What happens when ethyl isocyanide undergoes reduction?

Answer» `C_(2)H_(5)N-=C+H_(2) underset(Ni)to (C_(2)H_(5))-NH-CH_(3)`
156.

Which amine with formula `C_(3)H_(9)N` has least boiling point as compared to its other functional isomers?

Answer» Correct Answer - Trimethylamine
157.

Which of the following compound does not react with acety1 chloride ?A. `CH_(3)NH_(2)`B. `(CH_(23))_(2)N`C. `(CH_(3))_(2)NH`D. both (2) and (3)

Answer» Correct Answer - B
Primary and secondary amines can react with acid chlorides such as acety1 chloride to from substituted amindes in which `-Ci` has been replaced by th `-NHR` or `-NR_(2)` group
`CH_(3)NH_(2)+CH_(3)COCIoverset(-HCI)rarrCH_(3)NH-overset(O)overset(||)C-CH_(3)`
`(CH_(3))_(2)NH+CH_(3)COCIoverset(-HCI)rarr(CH_(3))_(2)NH-overset(O)overset(||)C-CH_(3)`
Tertiary amines (although basic and hence nucleophilic)fail to yield amides because they cannot lose a proton (to stabilize the product) a fter bonding themselves to electron-deficient carbon
`(CH_(3))_(3)N+CH_(3)COCI rarr`No reaction .
158.

The possible products are:A. B. C. D.

Answer» Correct Answer - A::C
159.

Reaction of aniline with acety1 chloride in the presence of `NaOH` gives .A. acetanilideB. p-chloroanilineC. a red dyeD. aniline hydrochloride

Answer» Correct Answer - A
It is acetylation of aniline the function of `NaOH` is to neutralize the `HCI` formed during the reaction:
`C_(6)H_(5)NH_(2)+CH_(3)COCIoverset(NaOH)rarrC_(6)H_(5)NHCOCH_(3)+HCI` .
160.

On reaction with `HNO_(2)C_(2)H_(5)NH_(2)` produces .A. `C_(2)H_(5)OH`B. `C_(2)H_(5)NO_(2)`C. `CH_(3)CHO`D. `CH_(3)COOH`

Answer» Correct Answer - A
Primary aliphatic amines such as `C_(2)H_(5)NH_(2)` react with nitrous acid to evolve `N_(2)` gas and yielding a mixture of products such as alcohlos halides etc
`C_(2)H_(5)NH_(2)+HONOrarrC_(2)H_(5)OH+N_(2)+H_(2)O` .
161.

Which is more basicA. BenzylamineB. AnilineC. AcetamideD. Benzamide

Answer» Correct Answer - A
Aralkylamines `(C_(6)H_(5)CH_(2)NH_(2))` are more basic than aromatic amines `(C_(6)H_(5)NH_(2))` which are more basic than anides The correct order of basic strenght is
`C_(6)H_(5)CH_(2)NH_(2)gtC_(6)H_(5)NH_(2)gtCH_(3)-overset(O)overset(||)C-NH_(2)gtC_(6)H_(5)CONH_(2)` .
162.

Why does acylation of `-NH_(2)` of aniline reduces its activating effect?

Answer» Due to electron withdrawing effect of the acetyl group, the lone pair of electron on N-atom is attracted by the `-overset(O)overset(||)C-` group. As a result, lone pair of electrons on N-atom is not exclusively available for donation to the benzene ring and hence activating effect of the `NH_(2)` group is reduced.
163.

Classify the following amines as primary, secondary or tertiary:(i) (C2H5)2CHNH2(ii) 

Answer»

(i) Primary Amine

(ii) Primary Amine

164.

NH3 is a Lewis base.

Answer»

Since nitrogen in ammonia molecule has a lone pair of electrons, it is a Lewis base.

165.

Under what reaction conditions (acidic/basic), the coupling reaction of aryldiazonium chloride with aniline is carried out?

Answer» Reaction is done in mild basic conditions.
166.

Arrange the following compounds in increasing order of dipole moment. CH3CH2CH3, CH3CH2NH2, CH3CH2OH

Answer»

CH3CH2CH3 < CH3CH2NH2 < CH3CH2OH

167.

Method by which Aniline can t be prepared is .A. reduction of nitrobenzene with `H_(2)Pd` in ethano1B. potassium salt of phthalimide treated with chlorobenzene followed by hydrolysis with aqueous `NaOH` solutionC. hydrolysis of phenyisocyanide with acidic solutionD. degradtion of benzamide with bromine in alkaline solution .

Answer» Correct Answer - B
Aromatic primary amines such as aniline can t be such as chlorobenzene do not easily undergo nucleophilic substitution with the anion formed by ppthalimide The inertness towards nucleophilic substitution is due to resonance which imparts double bond character to `C-X` bond .
168.

The following reaction is known by the name:A. Fridel-Crafts reactionB. Perkins reactionC. Acetylation reactionD. Schotten-Baumann reaction

Answer» Correct Answer - D
Schotten-Baumann reaction is a method to synthesise amides from amines and acid chlorides.
169.

Which diazonium salt is insoluble in water at room temprature?

Answer»

Benzene diazonium floro borate (C6H5N2F).

170.

In the following questions a statement of assertion followed by a statement of reason is given. Choose the correct answer out of the following choices.(i) Both assertion and reason are wrong.(ii) Both assertion and reason are correct statements but reason is not correct explanation of assertion.(iii) Assertion is correct statement but reason is wrong statement.(iv) Both assertion and reason are correct statements and reason is correct explanation of assertion.(v) Assertion is wrong statement but reason is correct statement.Assertion: Acetanilide is less basic than aniline.Reason: Acetylation of aniline results in decrease of electron density on nitrogen.

Answer»

(iv) Both assertion and reason are correct statements and reason is correct explanation of assertion.

171.

Write the IUPAC name of C6H6NHCH3.

Answer»

N - Methyl aniline.

172.

Which is more soluble in water, NH3 or methylamine?

Answer»

NH3 is more soluble in water due to more H-bonding.

173.

Arrange the following amines in the increasing order of their pKb values. Aniline, Cyclohexylamine, 4-Nitroaniline

Answer»

Cyclohexyl amine (pKA 3.34), aniline (pKA 9.13) 4-nitroaniline (pKA 12.99)

174.

Account for the following observation:1. Tertiary amine does not undergo acylation reaction2. Aniline readily reacts with bromine to give 2,4,6- tribromo aniline 

Answer»

1. Tertiary amine do not undergo acylation reaction because they do not contain a H-atom on the N-atom.

2. This is due to the strong activating effect of the amino group, Halogenation of amines occur very fast and halogens enter at all the three (one P-and two o-positions) positions even in the absence of the catalyst.

175.

Why is an alkyl amine more basic than ammonia?

Answer»

This is because of the presence of electron releasing alkyl group (positive I effect) which increases the electron density on nitrogen.

176.

The compound used for acylation of amine is :(a) (CH3CO)2O (b) CH3COOH (c) CH3COCl (d) both (a) and (c)

Answer»

Option : (d) both (a) and (c)

177.

Which of the following is a 3° amine?(i) 1-methylcyclohexylamine(ii) Triethylamine(iii) tert-butylamine(iv) N-methylaniline

Answer»

(ii) Triethylamine

178.

Which of the following cannot be prepared by Sandmeyer’s reaction?(i) Chlorobenzene(ii) Bromobenzene(iii) Iodobenzene(iv) Fluorobenzene

Answer»

(iii), (iv)

(iii) Iodobenzene

(iv) Fluorobenzene

179.

The correct IUPAC name for CH2=CHCH2 NHCH3 is(i) Allylmethylamine(ii) 2-amino-4-pentene(iii) 4-aminopent-1-ene(iv) N-methylprop-2-en-1-amine

Answer»

(iv) N-methylprop-2-en-1-amine

180.

When tetramethylammonium hydroxide is heated in aqueous solution under pressure the product is .A. `CH_(3)NH_(2)`B. `(CH_(3))_(2)NH`C. `(CH_(3))_(3)N`D. A mixture of all the three amines

Answer» Correct Answer - C
The decomposition proceeds according to the equation
`(CH_(3))_(4)overset(+)NOoverset(-)H overset(Delta)rarr(CH_(3))_(3)N+CH_(3)OH` .
181.

Assertion(A): N,N-diethylbenzene sulphonamide is insoluble in alkali. Reason(R ): Sulphonyl group attached to nitrogen atoms is strong electron withdrawing group.A. Both assertion and reason are worngB. Both assertion and reason are correct statement but reason is not correct explaination of assertion.C. Assertion is correct statements and reason is correct explanation of assertion.D. Both asseration and reason are correct statements and reason is correct explanation of assertion .

Answer» Both assertion and reason are correct and reason is not the correct explanation of assertion.
N, N-diethylbenene sulphonamide is insolube in alkali due to absence of acidic H attached to nitrogen .
182.

Explain the following reactions : (a) Gabriel Phthalimide reaction (b) Coupling reaction

Answer» The reaction of diazonium salts with phenols in basic medium (pH 9-10) and with `1^(2)` amines in acidic medium (pH 4-5) to give the corresponding azo dyes is called coupling reaction.
183.

Predict the product of following reaction: A. B. C. D.

Answer» Correct Answer - D
184.

Predict the nature of P in the following reaction: `Me_(3)C CH_(2)NH_(2) overset(HOMO)rarrP` (main product)A. `Me_(3)C CH_(2)OH`B. `Me_(2)C CH = CH_(2)`C. `Me_(2)C(OH)C_(2)H_(5)`D. `Me_(3)C CH_(2)NH(NO)`

Answer» Correct Answer - C
185.

Which of the following amines will react with cyclohexanone to give enamine?A. `CH_(3)NH_(2)`B. C. D.

Answer» Correct Answer - D
186.

The intermediates obtained in the reaction `overset(NaN_(3))underset("Heat")rarr R-NH_(2)` are:A. `R-overset(O)overset(||)(C)-bar(N)-overset(o+)(N)-=N`B. `R-N=C=O`C. `R-CNO`D. none of these

Answer» Correct Answer - A::B
187.

Compound `[X] C_(4)H_(11)N` reacts with p-toluence sulphonyl chloride in aqueous `NaOH` to give a solid. The compound [X] is:A. `CH_(3)-CH_(2)-CH_(2)-CH_(2)-NH_(2)`B. `H_(3)C-underset(CH_(3))underset(|)(CH)-CH_(2)-NH_(2)`C. `CH_(3)CH_(2)-NH-CH_(2)-CH_(3)`D. `H_(3)C-CH_(2)-underset(CH_(3))underset(|)(N)-CH_(3)`

Answer» Correct Answer - D
188.

Which of the following is least reactive toward complex formation with `BM_(3)` ?A. `NH_(3)`B. `Me_(3)N`C. `MeNH_(2)`D. `Me_(2)NH`

Answer» Correct Answer - B
The correct order of complex formation is
`Me_(2)NH gt MeNH_(2) gt NH_(3) gt gt Me_(3)N`
The first three amines are in the expected order because replacing `H` s by electron-donating alky1 groups make the amines more nucleophilic However another factore appears when `Me_(3)N` is involved The methyl groups on `B` hindering close approach of the two molecules and facilitating dissociation of the complex, if formed The net result is a slight drop in the complexation of the `3^(@)` amine This type of steric hindrance is called front strain (F-strain),since the hindrane occurs in fornt of the approaching molecules
189.

Which of the following give nitrosonamine on treatment with `HNO_(2)`?A. B. `H_(3)C-underset(CH_(3))underset(|)(CH)-CH_(2)-NH_(2)`C. D.

Answer» Correct Answer - A::C
190.

Which of the following can distinguish? `CH_(3)-overset(CH_(3))overset(|)(CH)-NH_(2)` and `CH_(3)-overset(H)overset(|)(N)-CH_(3)`A. `(COOC_(2)H_(5))_(2)`B. `NaNO_(2)+HCI`C. `Cs_(2),HgCI_(2)`D. `Ag_(2)O //Delta`

Answer» Correct Answer - A::B::C
191.

Which of the following ary1 halides is most reactive toward reaction with a primary amine ? .A. B. C. D.

Answer» Correct Answer - A
The presence of nitro groups at the ortho and para positions activates the ary1 halides towards neucleophilicsubstitution with primary amine The more the number of such groups the higher the reactivity .
192.

Which of the following compounds is most readily nitrated with `HNO_(3)` .?A. NitrobenzeneB. anilineC. Pheno1D. Benzene

Answer» Correct Answer - B
Nitro group is a deactivater while `NH_(2)` as well as `OH` groups are activators as `N` is less electronegative than oxygen atom This helps N to use its lone pair (for conjugation with the benzene ring) more effectively .
193.

Aniline dose not undergoA. Friedel Carafts alkylation Friedel Crafts alkylationB. Friedel Carafts acylationC. Both of theseD. None of these

Answer» Correct Answer - A
Aniline does not undergo Friedel-Crafts reaction (alkylation as well as acylation) due to salt formation with aluminium chloride the Lewis acid which is used as a catalyst to generate electrophile
`underset("Lewis base")(C_(6)H_(5)NH_(2))+ underset("Lewis acid")(AICI_(3))rarrC_(6)H_(5)underset(Sal t)overset(+)(NH_(2))-barAICI_(3)`
Due to this nitrogen of aniline acquires positive charge and hence acts as a strong deactivator for the electrophilic substitution Moreover `AICI_(3)` is not available to generate electrophile .
194.

By which of the following reactions can methylcyanide be prepared?A. `CH_(3)Broverset(KCN)underset(DMF)rarr`B. `CH_(3)NH_(2) +CHCI_(3) overset(KOH)rarr`C. `CH_(3)-CH=N-OH overset(P_(2)O_(5))underset(Delta)rarr`D. `CH_(3)-overset(O)overset(||)(C)-NH_(2)overset(P_(4)O_(10))underset(Delta)rarr`

Answer» Correct Answer - A::C::D
195.

Diazotisation can be carried out by the action of `NaNO_(2)` and dilute HCl at ice cold temperature onA. Aromatic secondary amineB. Aromatic primary amineC. Aromatic nitro compoundD. Aliphatic amine

Answer» Correct Answer - B
196.

Secondary amines could be prepared byA. reduction of nitro compoundsB. reduction of amidesC. reduction of isonitrilesD. reduction of isonitriles

Answer» Correct Answer - C::D
197.

Which of the following will not react with `CS_(2)`?A. `C_(6)H_(5)-NH_(2)`B. `CH_(5)-NH-CH_(3)`C. D.

Answer» Correct Answer - D
198.

Which of the following compounds can form alcohol with `NaNO_(2)//HCl`?A. B. C. `CH_(3)-CH_(2)-NH_(2)`D. All of these

Answer» Correct Answer - D
199.

A primary amine that can be obtained both by the reduction of cyanides and amides is(a) methyl amine (b) benzylamine (c) aniline (d) isopropylamine

Answer»

(b) benzylamine

200.

Which of the following compounds on hydrolysis yields a carboxylic acid?A. B. C. D.

Answer» Correct Answer - A::B::C::D