InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 151. |
Name the scientists associated with development of Golden RiceA. lngo Potrykus and Peter BeyerB. Milstein and KohlerC. Stanley Miller and Harold UreyD. Stanley Cohen and Herbert Boyer |
| Answer» Correct Answer - A | |
| 152. |
The first human hormone produced by recombinant DNA technology isA. InsulinB. EstrogenC. ThyroxinD. Progesterone |
| Answer» Correct Answer - A | |
| 153. |
Which of the following Bt crops is being grown in India by the farmers ?A. CottonB. BrinjalC. SoybeanD. Maize |
| Answer» Correct Answer - A | |
| 154. |
The first clinical gene therapy was given for treating :A. Adenosine deaminase deficiencyB. Diabetes mellitusC. Chicken poxD. Rheumatoid arthritis |
| Answer» Correct Answer - A | |
| 155. |
Name the classes of organisms that produce antibiotics. |
| Answer» The three common source of antibiotics are Eubacterialses actinomyceltales and fungi | |
| 156. |
Resistance to antibiotics is genetic trait that spreads naturally from one type of bacterium toA. almost from one type of bacterium toB. another bacterium of the same strainC. eukaryotic cells of all typesD. any other cell containing cope DNA |
| Answer» Correct Answer - C | |
| 157. |
Which of the following depicits white biotenchnology ?A. Agricultural processesB. Industrial processesC. Medical processesD. All of these |
| Answer» Correct Answer - B | |
| 158. |
How many amino acids are arranged in tow chains of insullin? |
| Answer» A moluecule of insulin cosists of two chains A and B The chain A has 21 amino acids and the chain B has 30 amino acids | |
| 159. |
How many amino acids are present in completely mature insulin? |
| Answer» Correct Answer - 51 amino acids | |
| 160. |
Correct the following statement giving reasons The mature insulin molicule consists of three short polypeptide chains |
| Answer» Hormone insulin is sythesized a s a proinsulin which consists of three polyepetide chain it undergoes a process of maturation during which the chain c consis ting of 33 amino acids is reoved the mature isulin molecule consist s of two shoert polypetpide chains of abut 51 amino acids the chain a ahs 21 and the chain B has 30 amino acids which are linked together by disulhide bridges | |
| 161. |
In a medical case it was detected that a child is suffereing form a genetic disroder due to the deletion to the gene. What remedial measure do you suggest for the treatment of such disorder ? |
| Answer» The best possible remedial measure is gnee t herapy in which a defective gene is manipulated by introducion of normal healty and fucntonal gene/s | |
| 162. |
Why is porinsulin so called ? How is insulin differnet form it? |
| Answer» Insulin used for diabetes was earlier extracted form pancras of slaughtered cattle and pigs insulin consists of two short polypeptide chains , chains , A and chain B that are linked together by disuclphide bridge in mammals including humans insulin is sytheseised as a prohoromoen(loke a pronezyme the pro hormones also need to be precessed before it becomved a fully matrue and functional hormone ) which contains an extra st rech called the c peptide | |
| 163. |
Explain how tansgenic animlas serve as model for human diseases? |
| Answer» Transgenic animlas contains functional foreign gense introduced into their genome form another specied by the technique of genetic engineering many of such transgenics are disigned to increse understndign and study of how genes contriubtes ot the development of disease these labroatroy exercises are specilly made to serve as models for human disease so the development of disease these laboratory exerciese are secially made t o seve as models for human diseases so that preventive measure and treatment for such deseases are made psosible | |
| 164. |
Explain how golden ric ecan prevent child blindness |
| Answer» Golden rice is a genetically modifed variety of erice it contains beta carotones is the building block of vitamin A deficiency of vitamin A causes blindness Thus beta carotein present in golden rice can prevent blindness in children | |
| 165. |
Assertion. The antibiotics produced by Streptomyces species have found greatest commercial application. Reason: Some of the important life saving antibiotics such as penicillia and polymixia-B are produced by streptomyces.A. If both Assertion and Reason are true and the Reason is a correct explanation of the AssertionB. If both Assertion and Reason are ture but Reason is not a correct explanation of the AssertionC. If Assertion is true but the Reason is falseD. If both Assertion and Reason are false |
| Answer» Correct Answer - C | |
| 166. |
A desirable change in genotype of an organism is obtained byA. DNA replicationB. protein synthesisC. rDNA technologyD. mRNA formation |
| Answer» Correct Answer - C | |
| 167. |
About what precentage of all existing transgenic animals are mice?A. 75B. 95C. 100D. 50 |
| Answer» Correct Answer - B | |
| 168. |
Who is responsible for obtaining interferons through recombinant DNA technique?A. A.R. BountingB. Eli LillyC. Charles Weissmann ·D. A. Tiselius |
| Answer» Correct Answer - C | |
| 169. |
Which one is wrong in relation to transgenic Bt cotton plantA. Crop yield loss due to attack by Bacillus thuringiensis bacterium is reducedB. Crop yield loss due to attack by lepidoperan insect pest is reducedC. Use of chemical insecticides in the cotton field is minimisedD. Better quality cotton is produced. |
| Answer» Correct Answer - A | |
| 170. |
More than 95 % of transgenic animals areA. rabbitsB. miceC. fishD. cows |
| Answer» Correct Answer - B | |
| 171. |
In view of the current food criis, it is said , that we need another green revolution. Highlight the major limitations of the eariler greeen revolution.. |
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Answer» Major limitations of the earlier green revolution are as follows. (i) Generally undersired characters also b reed alon g with desired ones. (ii) Regular use of fertilisers affected both soil fertlity and quality. ( iii) Extensive use of pesticides/insecticides/weedicides resulted in harmful effects on the natural compnents of the ecosystem. So, another green revolution that can curb these problems and enhance the quality food production in lim ited land resources is certainly required. |
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| 172. |
Which one of the following is a transgenic product useful for treatment of Haemophilia?A. Factor VIIIB. Antithrombin IIC. `alphA-1`-antitrypsinD. Lysostaphin |
| Answer» Correct Answer - A | |
| 173. |
which body of the government of india regulates GM reserch and safety of introducing GM organisms of public services ?A. Research Committee on Genetic ManipulationB. Bio-safety committeeC. Indian Concil of Agricultural ResearchD. Genetic Engineering Approval Committee |
| Answer» Correct Answer - D | |
| 174. |
Highlight any four areas where genetic modification of plants has been useful. |
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Answer» Genetically modified plants (GMOs) are the plants whose genes have been altered by manipulation. Genetically Modified Plants (GMOs) are the plants, whose genes have been altered by manipulation of plants is useful in different areas. Because of following reasons. (a) It increases tolerance agaisnt abiotic stresses (cold,drought,salt,heat) (b) it reduces reliance of chemical pesticides (pest-resitant crops). (c) it reduces post harvest losses. (d) it increases the efficiency of minerals used by plants (this prevents early exhaustion of fertility of soil). (e) It enhances nutritional value of food, e.g., vitamin-A enriched rice (goldenrice). (f) It creates tailor-made plants to supply alternative resources such as starch fuelds and pharmaceuticals to industries. |
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| 175. |
In India organisation responsible for assessing the safety of introducing genetically modified organisms for public use isA. indian council of medical research (IMCR)B. council for scientific and industiral research (CSIR)C. reasearch committee on genetic manipulation (RCGM)D. genetic engineering appraisal committee (GEAC) |
| Answer» Correct Answer - D | |
| 176. |
In vitro clonal propagation in plants is characterized byA. PCR and RAPDB. Northern blottingC. electrophoresis and HPLCD. microscopy |
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Answer» Correct Answer - A RAPD stand for Random Amplified Polymorphic DNA. It is a type of PCR reaction, but the segments of DNA that are amplified are random. Often, PCR is used to amplify a known DNA sequence. |
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| 177. |
A protoxin is:A. a primitive toxinB. a denatured toxinC. toxin produced by ProtozoaD. inactive toxin |
| Answer» Correct Answer - D | |
| 178. |
The inactive protoxin is activated in the gut of the insect by :A. acidic pHB. alkaline pHC. low temperatureD. high temperature |
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Answer» Correct Answer - B Bacillus thuringinensis forms a protein crystal (Cry ) during a particular phase of their growth. These crystals contains a toxic insecticidal protein. Bt toxin protein exists as an inactive protoxins, but once it ingests the inactive toxin, it is converted to the active form due to the alkaline pH of the gut which helps in solubilisation of these crystals. The activated toxin then binds to the surface of midgut epithelial cells, creating pores that causes cell swelling and lysis which leads to the death of the insects. |
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| 179. |
Which of the following is a second generation vaccine ?A. DPTB. CholeraC. Hepatitis -BD. None of these |
| Answer» Correct Answer - C | |
| 180. |
A protoxin isA. a primitive toxinB. a denatured toxinC. toxin produced by ProtozoeD. Inactive toxin. |
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Answer» A protein is an inactive toxin. The word pro in protons signifless inactive form B. thuringlensis forms protein crystal is which contain a toxic insecticidal protein (Bt toxin ). Bt toxins are initially protoxins but once ingested by insect, the inactive toxin. gets converted into an active form due to the alkaline pH of the put which solution the crystals. |
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| 181. |
Aprotoxin isA. a primitive toxinB. a denatured toxinC. toxin produced by protozoaD. inactive toxin |
| Answer» Correct Answer - d | |
| 182. |
Pathophysiology is theA. study of physiology of pathogenB. study of normal physiology of hostC. study of altered physiology of hostD. None of these |
| Answer» Correct Answer - C | |
| 183. |
Pathophysiology is theA. study of physiologyB. study of normal physiology hostC. study of altered physiology of hostD. None of these |
| Answer» Pathophysiology is the study of functional chan ges in the body of the host that occur is response to nay disease of injury. E.g. it someone are initially a toxin, a may result into a variety of physical changes, such as inflammation in the stomach linning. | |
| 184. |
The genetically -modified (GM) brinjal in India has been developed forA. insect-resistanceB. enchancing self lifeC. enchancing mineral contentD. drought-resistance |
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Answer» Correct Answer - A The genetically modifed brinjal or Bt brinjal has the same cry lac gene from Bacillus thurigiensis as cotton. The gene is supposed to make the plant tolerant to the shoot and fruit borer insect, which attachs it throughout its life cycle. |
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| 185. |
The genetically -modified (GM) brinjal in India has been developed forA. Drought-resistanceB. Insect-resistanceC. Enhancing shelf lifeD. Enhancing mineral content |
| Answer» Correct Answer - B | |
| 186. |
In ELISA TEST substance used isA. EndonudeaseB. LigaseC. PeroxidaseD. Polymerase |
| Answer» Correct Answer - C | |
| 187. |
Which of the following is a correct statementA. Bt in Bt cotton indicates that it is a genetically modified organism produced through biotechnologyB. somatic hybridization involves fusion of two coplete plant cells carrying desired genesC. the anticoagulant hirudin is being produced form transgenic brassica napus seedD. flaver savr variety of tomato has enhanced the producton of ethylene which improve its taste |
| Answer» Correct Answer - C | |
| 188. |
Bacillus thuringiensis (Bt) strains have been used for designing novelA. biofertilizersB. bio metallurgical techniquesC. bio mineraliztion processesD. bio insecticidal plants |
| Answer» Correct Answer - D | |
| 189. |
Bacillus thuringiensis (Bt) strains have been used for designing novelA. BiofertilizersB. Bio-metallurgical techniquesC. Bio-mineralization processesD. Bioinsecticidal plants |
| Answer» Correct Answer - D | |
| 190. |
Why is usually insulin not administered orally to a diabetic patient?A. Insulin is bitter is tasteB. Insulin is a peptideC. Insuline will lead to sudden decrease in blood sugar if given orallyD. Insulin leads to peptic ulcar if given orally |
| Answer» Correct Answer - C | |
| 191. |
Which Indian plants have either been patented or attempts have been made to patent them by western nations for their commercial use ?A. DaffodilB. NeemC. TurmericD. Both (2) & (3) |
| Answer» Correct Answer - D | |
| 192. |
Indian basmati was patented by us government asA. gene techB. basmati geneC. rice techD. Both (a) and (c ) |
| Answer» Correct Answer - C | |
| 193. |
Which Indian plants have either been patented or attempts have been made to patent them by western nations for their commercial use ?A. Basmati riceB. TurmericC. NeemD. All of these |
| Answer» Correct Answer - D | |
| 194. |
Name the Indian variety of rice patented by an American Company. |
| Answer» Indian variety of rice patented by american company Rice Tec in 1997 was basmati rice | |
| 195. |
How was insulin obtained before the adven t of rDNA technoloty? What were the problems encountered? |
| Answer» By polymersase chain Reaction Techgnique | |
| 196. |
A multinational company outside tried to sell new varieties of turmeric without proper patent rights. What is such an act referred to ? |
| Answer» Such an act is referred to biopiracy | |
| 197. |
Assertion : in recombinant DNA technology, human genes are often transferred into bacteria (prokaryotes) or yeast (eukaryote). Reason: Both bacteria and yeast multiply very fast to form huge population which express the desired gene.A. If both Assertion and Reason are true and the Reason is a correct explanation of the AssertionB. If both Assertion and Reason are ture but Reason is not a correct explanation of the AssertionC. If Assertion is true but the Reason is falseD. If both Assertion and Reason are false |
| Answer» Correct Answer - A | |
| 198. |
What is bio-piracy? State the initiative taken by the Indian Parliament against it |
| Answer» Use of bioresources with authorisatoin The government has celared patent t erms emergency provisions and also research and developemnt initivative | |
| 199. |
Bt cotton is notA. a GM plantB. insect resisdentC. a bacterial gene expressing systemD. resistant to all pesticides |
| Answer» Correct Answer - D | |
| 200. |
A bioreactor isA. fermentation tankB. culture of bacteriaC. hybridomaD. culture for synthesis of new chemicals |
| Answer» Correct Answer - A | |