80 + Interview Questions in Lipid Biosynthesis in Biochemistry Page 2 InterviewSolution

51.	Which of the following is a PLP-requiring enzyme?(a) Ornithine decarboxylase(b) Glutathione peroxidase(c) Glutamine synthase(d) Glutamate synthaseThe question was asked in an interview for job.My question is from Molecules Derived from Amino Acids in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Correct option is (a) Ornithine decarboxylase The BEST EXPLANATION: Ornithine decarboxylase is a pyridoxal PHOSPHATE (PLP) REQUIRING enzyme.

Discussion

52.	Which of the following transfers malonyl group from co-A to ACP?(a) Acyl carrier protein(b) Acetyl co-A ACP transacetylase(c) Enoyl-ACP reductase(d) Malonyl co-A ACP transferaseThis question was posed to me by my college professor while I was bunking the class.Asked question is from Biosynthesis of Fatty Acids and Eicosanoids topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» RIGHT choice is (d) Malonyl co-A ACP transferase For explanation I WOULD SAY: Acyl carrier protein carries acyl groups in thio-ester linkage. Acetyl co-A ACP transacetylase transfers acyl group from co-A to cys residue of KS. β-ketoacyl ACP synthase CONDENSES acyl and malonyl groups.

Discussion

53.	Which of the following transfers acyl group from co-A to cys residue of KS?(a) Acyl carrier protein(b) Acetyl co-A ACP transacetylase(c) Enoyl-ACP reductase(d) Malonyl co-A ACP transferaseI have been asked this question in an interview for internship.My enquiry is from Biosynthesis of Fatty Acids and Eicosanoids topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The CORRECT CHOICE is (b) Acetyl co-A ACP transacetylase Explanation: β-ketoacyl ACP SYNTHASE condenses acyl and malonyl groups. Malonyl co-A ACP transferase TRANSFERS malonyl GROUP from co-A to ACP. Acyl carrier protein carries acyl groups in thio-ester linkage.

Discussion

54.	Phosphorylation of AMP to ADP is promoted by ____________(a) Adenylate kinase(b) Aspartate transcarbamoylase(c) Dihyhroorotase(d) Cytidylate synthaseThis question was addressed to me during an interview.The doubt is from Biosynthesis and Degradation of Nucleotides in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The CORRECT answer is (a) Adenylate kinase Easy explanation: Phosphorylation of AMP to ADP is PROMOTED by adenylate kinase.

Discussion

55.	Which of the following gives rise to γ-amino butyrate?(a) Glutamate synthase(b) Glutamate decarboxylation(c) Glutamine synthase(d) Pyruvate decarboxylationThe question was posed to me in exam.I'd like to ask this question from Molecules Derived from Amino Acids in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Right answer is (b) Glutamate DECARBOXYLATION Explanation: Glutamate decarboxylation GIVES RISE to γ-amino butyrate.

Discussion

56.	The prosthetic group of acyl carrier protein is ___________(a) 4’-phosphopantetheine(b) 3’-phosphopantetheine(c) 2’-phosphopantetheine(d) 1’-phosphopantetheineThe question was asked in semester exam.Asked question is from Biosynthesis of Fatty Acids and Eicosanoids in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» RIGHT answer is (a) 4’-phosphopantetheine The best I can EXPLAIN: ACYL protein carrier (ACP) is a small protein CONTAINING the prosthetic group 4’-phosphopantetheine.

Discussion

57.	Which of the following is derived from tryptophan?(a) Dopamine(b) Norepinephrine(c) Epinephrine(d) SerotoninThis question was addressed to me in an interview for job.My doubt is from Molecules Derived from Amino Acids in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» CORRECT answer is (d) Serotonin To explain: Dopamine, norepinephrine and EPINEPHRINE are DERIVED from TYROSINE.

Discussion

58.	Precursor of glycine is ____________(a) Proline(b) Glutamine(c) Serine(d) GlutamateThe question was asked in final exam.I'd like to ask this question from Biosynthesis of Amino Acids topic in chapter Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct CHOICE is (C) Serine Best explanation: PRECURSOR of GLYCINE and CYSTEINE is serine.

Discussion

59.	Dinitrogenase reductase is a ____________(a) Monomer(b) Dimer(c) Trimer(d) TetramerI have been asked this question during an internship interview.Question is from Overview of Nitrogen Metabolism topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Correct option is (B) DIMER For EXPLANATION: Dinitrogenase REDUCTASE is a dimer of two identical subunits.

Discussion

60.	Lignin is derived from ____________(a) Phenylalanine(b) Valine(c) Tryptophan(d) ArginineI have been asked this question by my college professor while I was bunking the class.This interesting question is from Molecules Derived from Amino Acids in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» RIGHT answer is (a) PHENYLALANINE To explain: LIGNIN is derived from phenylalanine and TYROSINE.

Discussion

61.	Which of the following is not an aromatic amino acid?(a) Phenylalanine(b) Tyrosine(c) Tryptophan(d) LeucineI have been asked this question during an online exam.My question is from Biosynthesis of Amino Acids topic in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The CORRECT OPTION is (d) LEUCINE Best EXPLANATION: Leucine is a non-aromatic amino acid.

Discussion

62.	Which of the following catalyzes reactions that incorporate nitrogen derived from glutamine?(a) Glutamine amidotransferase(b) Adenylyltransferase(c) Glutamate synthase(d) Glutamine synthaseThis question was addressed to me during an internship interview.The above asked question is from Overview of Nitrogen Metabolism topic in chapter Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» RIGHT answer is (a) Glutamine amidotransferase For explanation: Glutamine amidotransferase CATALYZES reactions that incorporate nitrogen DERIVED from glutamine.

Discussion

63.	Nitrate is reduced and ultimately produces N2 through a series of intermediate gaseous nitrogen oxide products is called ____________(a) Nitrogen fixation(b) Nitrification(c) Denitrification(d) Nitrogen assimilationI have been asked this question in examination.My doubt stems from Overview of Nitrogen Metabolism in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Right choice is (c) Denitrification Explanation: CONVERSION of NITROGEN to ammonia or nitrogenous compounds is termed as nitrogen fixation. Formation of organic nitrogen compounds like AMINO acids from inorganic nitrogen compounds is CALLED nitrogen assimilation. Ammonia or AMMONIUM is oxidized to nitrite followed by the oxidation of nitrite to nitrate is called nitrification.

Discussion

64.	Which of the following is the integral membrane protein of smooth ER?(a) Thiolase(b) HMG co-A synthase(c) HMG co-A reductase(d) Pyruvate kinaseI had been asked this question in examination.This interesting question is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Right OPTION is (c) HMG co-A REDUCTASE The explanation: HMG co-A reductase is the INTEGRAL membrane protein of SMOOTH ER.

Discussion

65.	Phosphatidylserine is derived only from ___________(a) Phosphatidylethanolamine(b) Phosphatidyl glycerol(c) Phosphatidyl choline(d) CDP-diacylglycerolThe question was posed to me in an interview for internship.I'd like to ask this question from Biosynthesis of Membrane Phospholipids in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Right ANSWER is (a) Phosphatidylethanolamine Easy EXPLANATION: Decarboxylation of phosphatidylserine PRODUCES phosphatidylethanolamine.

Discussion

66.	Where does the triacylglycerol form?(a) Liver(b) Kidneys(c) Adipose tissue(d) HeartI got this question during an interview.The above asked question is from Biosynthesis of Triacylglycerols in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Correct answer is (a) Liver For explanation: Triacylglycerol FORMED in the liver is TRANSPORTED in the BLOOD back to ADIPOSE tissue.

Discussion

67.	Conversion of dUMP to dTMP is catalyzed by ____________(a) Thymidylate synthase(b) Dihydrofolate reductase(c) Dihyhroorotase(d) Cytidylate synthaseThe question was asked in an interview for internship.Question is taken from Biosynthesis and Degradation of Nucleotides in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Right ANSWER is (a) Thymidylate SYNTHASE Best EXPLANATION: CONVERSION of dUMP to dTMP is catalyzed by thymidylate synthase.

Discussion

68.	CTP is formed from UTP by the action of ____________(a) Adenylate kinase(b) Aspartate transcarbamoylase(c) Dihyhroorotase(d) Cytidylate synthaseI had been asked this question in an interview.The above asked question is from Biosynthesis and Degradation of Nucleotides topic in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Right answer is (d) Cytidylate SYNTHASE For explanation: CTP is FORMED from UTP by the action of cytidylate synthase.

Discussion

69.	In the first committed step of pyrimidine biosynthesis, the reaction is catalyzed by ____________(a) Adenylate kinase(b) Aspartate transcarbamoylase(c) Dihyhroorotase(d) Cytidylate synthaseI got this question in an online interview.Question is from Biosynthesis and Degradation of Nucleotides topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» CORRECT answer is (b) Aspartate transcarbamoylase To explain I would say: Carbamoyl PHOSPHATE reacts with aspartate to yield N-carbamoylaspartate in the FIRST COMMITTED STEP of pyrimidine biosynthesis catalyzed by aspartate transcarbamoylase.

Discussion

70.	Glutathione peroxidase contains a covalently bound ____________(a) Selenium atom(b) Calcium atom(c) Magnesium atom(d) Copper atomI got this question in quiz.My doubt is from Molecules Derived from Amino Acids topic in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct answer is (a) SELENIUM atom Best explanation: GLUTATHIONE peroxidase CONTAINS a covalently bound selenium atom.

Discussion

71.	Which of the following is the precursor for auxin?(a) Phenylalanine(b) Valine(c) Tryptophan(d) ArginineThis question was posed to me in an online quiz.The question is from Molecules Derived from Amino Acids in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Correct CHOICE is (C) Tryptophan Explanation: Tryptophan is the precursor for AUXIN.

Discussion

72.	Tyrosine gives rise to a family of catecholamines that does not include ____________(a) Dopamine(b) Norepinephrine(c) Epinephrine(d) CortisolThis question was addressed to me during an internship interview.Question is from Molecules Derived from Amino Acids topic in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct OPTION is (d) Cortisol To explain I would say: Tyrosine GIVES rise to a family of CATECHOLAMINES that INCLUDES DOPAMINE, norepinephrine and epinephrine.

Discussion

73.	Which of the following is the major point of regulation on the pathway to cholesterol?(a) Thiolase(b) HMG co-A synthase(c) HMG co-A reductase(d) Pyruvate kinaseI had been asked this question during a job interview.The doubt is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct option is (c) HMG co-A reductase To explain I WOULD say: HMG co-A reductase is the major POINT of REGULATION on the PATHWAY to cholesterol.

Discussion

74.	Prednisolone and prednisone are chemically ___________(a) Steroids(b) Glycerol derivatives(c) Non-steroid anti-inflammatory drug(d) Amino alcoholsThe question was asked in an international level competition.Query is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in chapter Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» CORRECT answer is (a) Steroids Easiest EXPLANATION: PREDNISOLONE and PREDNISONE are chemically steroids.

Discussion

75.	Generally, the receptors for steroid hormones reside at ___________(a) Nucleoplasm(b) Nuclear membrane(c) Cytoplasm(d) Plasma membraneThe question was asked in class test.This interesting question is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in division Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct answer is (a) NUCLEOPLASM Explanation: The RECEPTORS for STEROID HORMONES RESIDE at nucleoplasm.

Discussion

76.	Which of the following converts PGH2 to thromboxane A2?(a) Enoyl-ACP reductase(b) β-ketoacyl ACP reductase(c) Cyclooxygenase(d) Thromboxane synthaseThe question was posed to me during a job interview.My question is based upon Biosynthesis of Fatty Acids and Eicosanoids in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Correct choice is (d) Thromboxane SYNTHASE To explain I would say: Thromboxane synthase PRESENT in blood platelets CONVERTS PGH2 to thromboxane A2.

Discussion

77.	Formation of organic nitrogen compounds like amino acids from inorganic nitrogen compounds is called as ____________(a) Nitrogen fixation(b) Nitrification(c) Denitrification(d) Nitrogen assimilationI had been asked this question during an interview.I need to ask this question from Overview of Nitrogen Metabolism in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct choice is (d) Nitrogen assimilation To explain I would SAY: Ammonia or ammonium is oxidized to nitrite followed by the oxidation of nitrite to nitrate is called nitrification. Nitrate is reduced and ultimately produces N2 through a SERIES of intermediate gaseous nitrogen oxide products is called denitrification. Conversion of nitrogen to ammonia or NITROGENOUS COMPOUNDS is termed as nitrogen fixation.

Discussion

78.	How many carbons are present in geranyl pyrophosphate?(a) 8(b) 9(c) 10(d) 11I got this question in an international level competition.The query is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in portion Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» The correct answer is (C) 10 To explain: Geranyl PYROPHOSPHATE is a 10-carbon CHAIN.

Discussion

79.	Which of the following regulates the female reproductive cycle?(a) Progesterone(b) Testosterone(c) Estrogens(d) GlucocorticoidsI got this question in semester exam.My question is based upon Biosynthesis of Cholesterol, Steroids and Isoprenoids topic in chapter Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» Correct ANSWER is (a) Progesterone For explanation I WOULD say: Testosterone and estrogens which influence the development of secondary SEXUAL CHARACTERISTICS in males and females, respectively. Glucocorticoids HELP regulate gluconeogenesis and reduce the inflammatory response.

Discussion

80.	Which of the following class of drugs reduce the levels of fatty acids circulating in the blood?(a) Thiazolidinediones(b) Amphetamines(c) Cathinones(d) Synthetic cannabinoidsI got this question in an internship interview.My question is based upon Biosynthesis of Triacylglycerols topic in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry
Answer» RIGHT choice is (a) THIAZOLIDINEDIONES Explanation: Thiazolidinediones REDUCE the levels of fatty acids circulating in the blood and INCREASE sensitivity to insulin.

Discussion

Explore topic-wise InterviewSolutions in .

Precursor of glycine is ____________(a) Proline(b) Glutamine(c) Serine(d) GlutamateThe question was asked in final exam.I'd like to ask this question from Biosynthesis of Amino Acids topic in chapter Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Where does the triacylglycerol form?(a) Liver(b) Kidneys(c) Adipose tissue(d) HeartI got this question during an interview.The above asked question is from Biosynthesis of Triacylglycerols in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry