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Which of the following is the major point of regulation on the pathway to cholesterol?(a) Thiolase(b) HMG co-A synthase(c) HMG co-A reductase(d) Pyruvate kinaseI had been asked this question during a job interview.The doubt is from Biosynthesis of Cholesterol, Steroids and Isoprenoids in section Lipid Biosynthesis, Biosynthesis of Amino Acids, Nucleotides and Related Molecules of Biochemistry

Answer»

The correct option is (c) HMG co-A reductase

To explain I WOULD say: HMG co-A reductase is the major POINT of REGULATION on the PATHWAY to cholesterol.



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