100 + Interview Questions in Biosignalling in Biochemistry Page 1 InterviewSolution

1.	Which of the following occurs in meiosis but not in mitosis?(a) Attachment of spindle fibers to kinetochore(b) Replication of DNA prior to start of cell division(c) Separation of sister chromatids at anaphase(d) Pairing of homologous chromosomes at metaphase plateThis question was posed to me in examination.Origin of the question is Regulation of the Cell Cycle by Protein Kinases topic in portion Biosignalling of Biochemistry
Answer» Right option is (d) Pairing of homologous CHROMOSOMES at metaphase PLATE The EXPLANATION: Pairing of homologous chromosomes at metaphase plate does not occur in MITOSIS.

Discussion

2.	Which of the following statements regarding cyclins is not correct?(a) They can become linked to ubiquitin(b) They catalyze the phosphorylation of protein(c) They contain a specific amino acid sequence that target them for proteolysis(d) They are activated and degraded during cell cycleThe question was posed to me during a job interview.Question is taken from Regulation of the Cell Cycle by Protein Kinases topic in section Biosignalling of Biochemistry
Answer» RIGHT choice is (d) They are ACTIVATED and DEGRADED during cell cycle Easy explanation: They activate CDK enzymes.

Discussion

3.	A factor involved in regulating the fate of stem cells in plant development is _________(a) Adrenaline(b) Epinephrine(c) Thyroid stimulating hormone(d) CLV1The question was asked in examination.Question is from Signaling in Microorganisms and Plants topic in division Biosignalling of Biochemistry
Answer» The CORRECT OPTION is (d) CLV1 To elaborate: Adrenaline, EPINEPHRINE and thyroid stimulating hormones are animal hormones.

Discussion

4.	Which of the following is involved in extrinsic cell death pathway?(a) Heterotrimeric G protein complex(b) TRADD(c) IRS-1(d) Protein-kinase AThe question was posed to me by my school teacher while I was bunking the class.My question is based upon Multivalent Scaffold Proteins and Membrane Rafts topic in chapter Biosignalling of Biochemistry
Answer» Correct choice is (b) TRADD The BEST I can EXPLAIN: TRADD, TUMOR NECROSIS factor receptor type 1-associated death DOMAIN protein is involved in extrinsic cell death pathway.

Discussion

5.	A hormone or ligand can be considered as ___________(a) First messenger(b) Second messenger(c) Third messenger(d) Fourth messengerThe question was posed to me in semester exam.This is a very interesting question from G Protein in section Biosignalling of Biochemistry
Answer» Correct ANSWER is (a) First messenger The EXPLANATION is: Hormones are often considered to be first MESSENGERS, IP3, cAMP and cGMP are considered to be SECOND messengers.

Discussion

6.	The binding of ligands to many GPCRs leads to ___________(a) Decrease in concentration of certain intracellular signal molecules called second messengers(b) Increase in concentration of certain intracellular signal molecules called second messengers(c) Decrease in concentration of certain extracellular signal molecules called first messengers(d) Increase in concentration of certain extracellular signal molecules called first messengersI have been asked this question in an online quiz.This interesting question is from G Protein in section Biosignalling of Biochemistry
Answer» Right option is (a) Decrease in CONCENTRATION of certain intracellular signal molecules CALLED second messengers For EXPLANATION: The BINDING of LIGANDS to many GPCRs leads to decrease in concentration of second messengers.

Discussion

7.	Nicotinic acetylcholine receptor is an example of _____________(a) Ligated gated receptor channel(b) Serpentine receptors(c) Adhesion receptors(d) Receptor enzymesI had been asked this question in unit test.This intriguing question originated from Gated Ion Channels topic in chapter Biosignalling of Biochemistry
Answer» The correct ANSWER is (a) Ligated gated RECEPTOR channel The EXPLANATION: NICOTINIC acetylcholine receptor is an EXAMPLE of ligated gated receptor channel.

Discussion

8.	Proto-oncogenes can be transformed to oncogenes by all of the following mechanisms except _____________(a) Elimination of their start signals for translation(b) During a viral infection cycle(c) Chromosomal rearrangements(d) Chemically induced mutagenesisThis question was addressed to me in an interview for job.This intriguing question originated from Oncogenes, Tumor Suppressor Genes and Programmed Cell Death topic in portion Biosignalling of Biochemistry
Answer» Correct option is (a) ELIMINATION of their start SIGNALS for translation Easy EXPLANATION: Elimination of their start signals cannot PROMOTE cancer.

Discussion

9.	Which out of the following statements about sense of smell is not true?(a) Olfactory receptor cells are bipolar neurons, not replaced when damaged(b) The chemicals are received by specific plasma membrane receptors in olfactory receptor cells(c) Olfactory receptors do not adapt quickly(d) The main areas of brain that interpret sense of smell be in the temporal and frontal lobesI got this question by my school teacher while I was bunking the class.Enquiry is from Sensory Transduction in Vision, Olfaction and Gustation in division Biosignalling of Biochemistry
Answer» Correct option is (c) OLFACTORY receptors do not adapt quickly The explanation is: Olfactory receptors adapt quickly, the ODOR seems to be less powerful after a few MINUTES of EXPOSURE.

Discussion

10.	Plasma membrane protein predicted to have seen 7 transmembrane helices segment binds __________(a) Progesterone(b) Thyroid stimulating hormone(c) Insulin(d) Follicle stimulating hormoneI have been asked this question in class test.The query is from Regulation of Transcription by Steroid Hormones in portion Biosignalling of Biochemistry
Answer» The CORRECT answer is (a) PROGESTERONE For EXPLANATION: Progesterone hormone is a steroid hormone, can DIFFUSE through cell membranes.

Discussion

11.	Mode of action of steroid hormones involve ______________(a) Stimulation of DNA replication(b) Stimulation of m-RNA transcription(c) Inhibition of protein synthesis(d) Secondary messengerThis question was posed to me by my college professor while I was bunking the class.Question is taken from Regulation of Transcription by Steroid Hormones topic in portion Biosignalling of Biochemistry
Answer» Right option is (b) Stimulation of m-RNA transcription The best I can EXPLAIN: STEROID hormones involve in the stimulation of m-RNA transcription, AFFECTING the gene expression.

Discussion

12.	What is the drug antagonist of estrogen?(a) Tanoxifen(b) Metformin(c) Glucophage(d) VictozaThe question was asked in a national level competition.The query is from Regulation of Transcription by Steroid Hormones topic in chapter Biosignalling of Biochemistry
Answer» CORRECT OPTION is (a) Tanoxifen For EXPLANATION: Tanoxifen is an ANTAGONIST of ESTROGEN.

Discussion

13.	ERF1is a _________(a) Translation terminating factor(b) Positive regulator(c) Translation promoting factor(d) Enzyme inhibitorI have been asked this question in exam.The question is from Signaling in Microorganisms and Plants topic in section Biosignalling of Biochemistry
Answer» Right answer is (a) Translation TERMINATING FACTOR To ELABORATE: ERF1 is a eukaryotic translation terminating factor.

Discussion

14.	Which of the following about Rb tumor suppressor protein is correct?(a) It binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received(b) It is activated when phosphorylated by Cdk(c) It is a transcription factor(d) When a mitogenic signal is received, it binds the transcription factor E2F and thus stimulates the cell to enter S phaseThis question was addressed to me in examination.Origin of the question is Oncogenes, Tumor Suppressor Genes and Programmed Cell Death in division Biosignalling of Biochemistry
Answer» Right option is (a) It binds E2F transcription factor and PREVENTS cell from ENTERING S phase until a mitogenic signal is received To explain I would SAY: RB protein binds E2F transcription factor and prevents cell from entering S phase until a mitogenic signal is received.

Discussion

15.	Steroid regulatory proteins mediate the act by binding at ___________(a) Zinc finger motif(b) Leucine zipper motif(c) Helix turn helix motif(d) Histone helix motifThis question was posed to me in an interview for job.The origin of the question is Regulation of Transcription by Steroid Hormones topic in chapter Biosignalling of Biochemistry
Answer» The correct answer is (a) ZINC FINGER motif The best EXPLANATION: STEROID regulatory proteins mediate the ACT by binding at zinc finger motif.

Discussion

16.	In Arabidopsis flg22 binds to _________(a) FLS2(b) LPS(c) BAK1(d) MAPKThis question was posed to me by my college director while I was bunking the class.I want to ask this question from Signaling in Microorganisms and Plants topic in section Biosignalling of Biochemistry
Answer» The correct answer is (a) FLS2 Easiest EXPLANATION: flg22 PRESENT in PLANTS binds to FLS2.

Discussion

17.	Scaffold protein in insulin signal transduction ___________(a) KSR(b) IRS-1(c) MEKK1(d) AKAPI had been asked this question in exam.The query is from Multivalent Scaffold Proteins and Membrane Rafts topic in portion Biosignalling of Biochemistry
Answer» RIGHT option is (B) IRS-1 The EXPLANATION is: IRS-1 is an adapter PROTEIN in insulin that codes for IRS1 gene.

Discussion

18.	Which out of the following statements is true about G-protein couple receptors?(a) The N-terminal chain is extracellular and C-terminal chain is intracellular(b) It contains 5 trans-membrane hydrophobic sections(c) There are more extracellular loops than intracellular loops(d) The binding region for G-protein involves 2 extracellular loopsThe question was posed to me in an online interview.The origin of the question is G Protein in chapter Biosignalling of Biochemistry
Answer» CORRECT ANSWER is (a) The N-terminal chain is extracellular and C-terminal chain is INTRACELLULAR Best EXPLANATION: GPCR is characterized by an extracellular N-terminus and an intracellular C-terminus.

Discussion

19.	Which of the following statements is false about a ligand-gated ion channel receptor?(a) They are present in the cell membrane(b) They consist of five glycoproteins(c) Differences in membrane potential affect whether the channel receptors are open or close(d) Neurotransmitters can act as the chemical messengers for these channelsI had been asked this question in an online interview.This key question is from Gated Ion Channels in chapter Biosignalling of Biochemistry
Answer» Right choice is (C) Differences in MEMBRANE potential affect whether the channel receptors are open or close To explain: Ligands affect whether the channel receptors are open or close in a ligand-gated ion channel whereas VOLTAGE gated ion CHANNELS are CONTROLLED by the differences in membrane potential affect.

Discussion

20.	Which of the following is a nuclear receptor protein?(a) Steroid receptor(b) Adhesion receptor(c) Serpentine receptor(d) Receptor with no intrinsic enzyme activityThe question was posed to me in examination.This key question is from Molecular Mechanisms of Signal Transduction topic in section Biosignalling of Biochemistry
Answer» The correct CHOICE is (a) STEROID RECEPTOR Easiest EXPLANATION: Steroid receptor is a nuclear receptor protein.

Discussion

21.	Steroid hormones receptor binds to _____________(a) Hormone response elements in m-RNA(b) Hormone response elements in DNA(c) Hormone response elements in proteins(d) Ribosomes to stimulate translationThis question was addressed to me in homework.Question is from Regulation of Transcription by Steroid Hormones in portion Biosignalling of Biochemistry
Answer» Right OPTION is (B) Hormone response ELEMENTS in DNA Best EXPLANATION: Hormone response elements are short sequence of DNA where steroid hormone RECEPTORS bind.

Discussion

22.	How do steroid hormones produce their effects in cells?(a) By activating key enzymes in metabolic pathway(b) By binding to intracellular receptors and promoting transcription of specific genes(c) By promoting the degradation of specific m-RNAs(d) By activating translation of certain m-RNAsThe question was asked during an online exam.My enquiry is from Regulation of Transcription by Steroid Hormones in portion Biosignalling of Biochemistry
Answer» Right option is (b) By binding to intracellular receptors and PROMOTING transcription of specific genes Explanation: Steroid HORMONES PRODUCE their EFFECTS in CELLS by binding to intracellular receptors and promoting transcription of specific genes.

Discussion

23.	The specificity of signaling pathways does not include ___________(a) Migration of signal proteins into membrane rafts(b) Assembly of large multiprotein complexes(c) Phosphorylation of target proteins at Ser, Thr/Tyr residues(d) Flippase-catalyzed movement of phospholipids from the inner to the outer leafletThe question was posed to me by my school teacher while I was bunking the class.I'm obligated to ask this question of Multivalent Scaffold Proteins and Membrane Rafts topic in chapter Biosignalling of Biochemistry
Answer» Correct answer is (d) Flippase-catalyzed movement of phospholipids from the inner to the outer leaflet To EXPLAIN I would say: The specificity of SIGNALING PATHWAYS does not INCLUDE flippase-catalyzed movement of phospholipids from the inner to the outer leaflet.

Discussion

24.	The enzyme activated by cyclic AMP, passing on the hormonal signal is ____________(a) Protein kinase B(b) Protein kinase A(c) Protein kinase C(d) G protein receptor kinaseThis question was posed to me in an internship interview.The above asked question is from Receptor Enzymes in section Biosignalling of Biochemistry
Answer» Correct answer is (B) Protein KINASE A Easiest explanation: Protein kinase A is activated by CYCLIC AMP, passing on the HORMONAL signal.

Discussion

25.	The receptor channels for which of the following are gated by extracellular ligands?(a) Glycine(b) IP3(c) cAMP(d) cGMPThe question was posed to me in unit test.The doubt is from Gated Ion Channels topic in chapter Biosignalling of Biochemistry
Answer» Correct answer is (a) Glycine To EXPLAIN: The RECEPTOR channels for glycine are gated by extracellular ligands.

Discussion

26.	Receptor is removed from cell surface in _____________(a) Specificity(b) Amplification(c) Adaptation(d) IntegrationThis question was addressed to me in an interview for internship.My doubt stems from Molecular Mechanisms of Signal Transduction topic in section Biosignalling of Biochemistry
Answer» Correct answer is (c) Adaptation The best explanation: A regulatory outcome result from INTEGRATED input from both receptors is in integration. Signal molecule fits its binding site on its COMPLEMENTARY receptor called as specificity. Number of affected molecules increases geometrically in an enzyme CASCADE in AMPLIFICATION.

Discussion

27.	At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damaged?(a) G1 – S(b) S – G2(c) G2 – M(d) G0 – G1I got this question during an interview.Asked question is from Regulation of the Cell Cycle by Protein Kinases topic in division Biosignalling of Biochemistry
Answer» Right answer is (a) G1 – S Best EXPLANATION: During G1 phase cell grows and during S phase DNA replicates. So there MUST be a CHECKPOINT between these two phases to check if there is a DAMAGE in DNA.

Discussion

28.	Which is an example of a positive regulator?(a) CAP(b) Lac 1 gene(c) Trp operon(d) Met operonThe question was posed to me during an interview.Asked question is from Regulation of Transcription by Steroid Hormones topic in portion Biosignalling of Biochemistry
Answer» Correct ANSWER is (a) CAP To explain: LAC 1 GENE, Trp operon and Met operon are NEGATIVE regulators.

Discussion

29.	The G protein involved in visual signal transduction is _________(a) Rhodopsin(b) GTP receptor(c) Arrestin(d) TransducinThe question was posed to me during an interview for a job.I would like to ask this question from Sensory Transduction in Vision, Olfaction and Gustation in section Biosignalling of Biochemistry
Answer» Right CHOICE is (C) Arrestin To explain: RHODOPSIN is INVOLVED in visual SIGNAL transduction.

Discussion

30.	Transcription factor in plants is _________(a) Serine(b) Threonine(c) WRKY22/29(d) LeucineThe question was asked during an online interview.I'd like to ask this question from Signaling in Microorganisms and Plants in section Biosignalling of Biochemistry
Answer» The CORRECT choice is (C) WRKY22/29 To EXPLAIN: Serine, threonine and LEUCINE are amino ACIDS.

Discussion

31.	Which of the following converts GTP to cGMP to start its enzymatic cascade?(a) Receptor guanylyl cyclase(b) Receptor adenylyl cyclase(c) Calmodulin(d) Protein kinase-AThis question was posed to me by my college professor while I was bunking the class.Enquiry is from Multivalent Scaffold Proteins and Membrane Rafts topic in portion Biosignalling of Biochemistry
Answer» Right OPTION is (a) Receptor guanylyl cyclase The EXPLANATION: Receptor adenylyl cyclase converts ATP to cAMP.

Discussion

32.	Which of the following serves as a neurotransmitter in adrenergic neurons?(a) Serotonin(b) Epinephrine(c) Dopamine(d) HistamineI had been asked this question in an internship interview.This question is from G Protein topic in division Biosignalling of Biochemistry
Answer» Correct answer is (b) EPINEPHRINE The EXPLANATION is: ADRENALINE or epinephrine SERVES as a neurotransmitter in adrenergic neurons.

Discussion

33.	Regulatory outcome results from integrated input from both receptors is in _____________(a) Specificity(b) Amplification(c) Adaptation(d) IntegrationThe question was asked by my school teacher while I was bunking the class.The query is from Molecular Mechanisms of Signal Transduction topic in portion Biosignalling of Biochemistry
Answer» The CORRECT option is (d) Integration Easy explanation: Receptor is removed from CELL surface in adaptation. Signal molecule FITS binding site on its complementary receptor called as specificity. Number of affected MOLECULES INCREASES geometrically in an enzyme cascade in amplification.

Discussion

34.	The mutation which cannot give rise to an oncogene?(a) Addition or deletion of a base producing a nonsense message and an inactive protein product(b) A point mutation changing just one amino acid in protein product(c) A translocation, putting gene under control of strong promoter producing over expression(d) A point mutation producing stop codon, premature terminationThis question was posed to me in final exam.This key question is from Oncogenes, Tumor Suppressor Genes and Programmed Cell Death topic in section Biosignalling of Biochemistry
Answer» RIGHT answer is (a) Addition or deletion of a base PRODUCING a nonsense MESSAGE and an inactive PROTEIN product Explanation: Addition or deletion of a base producing a nonsense message and an inactive protein product cannot produce an oncogene.

Discussion

35.	When visual stimulus reaches receptors in retina of eye, second process involving absorption of physical energy by receptors is?(a) Reception(b) Transduction(c) Coding(d) AdaptationThis question was addressed to me in an online interview.My doubt is from Sensory Transduction in Vision, Olfaction and Gustation in section Biosignalling of Biochemistry
Answer» Correct OPTION is (b) TRANSDUCTION Explanation: Transduction is the second process involved in the absorption of physical energy by receptors when visual stimulus REACHES receptors in retina of eye.

Discussion

36.	What is the relationship between olfactory sensors and gustatory sensors?(a) Gustatory hair can also detect odorants(b) Olfactory hair can also detect tastants(c) Olfactory sensors provides information about substance that we are about to taste(d) No relationThis question was posed to me in an online interview.Enquiry is from Sensory Transduction in Vision, Olfaction and Gustation in division Biosignalling of Biochemistry
Answer» The CORRECT CHOICE is (c) Olfactory sensors provides information about substance that we are about to taste The explanation: The taste of FOOD is partially due to food molecules STIMULATING olfactory receptors in the nose other than GUSTATORY sensors in the mouth.

Discussion

37.	Most olfactory receptors are located on the _________(a) Superior surface of nasal cavity(b) Interior surface of nasal cavity(c) Lateral surface of nasal cavity(d) Medial surface of nasal cavityThe question was asked in examination.I'm obligated to ask this question of Sensory Transduction in Vision, Olfaction and Gustation topic in chapter Biosignalling of Biochemistry
Answer» CORRECT OPTION is (a) SUPERIOR surface of NASAL cavity Explanation: Most olfactory receptors are located on the superior surface of nasal cavity.

Discussion

38.	The peptide trigger for the self-incompatibility response that prevents self-pollination is _________(a) Salicylic acid(b) Jasmonates(c) Brassinosteroids(d) Plant peptide hormonesThis question was posed to me in an interview.Question is from Signaling in Microorganisms and Plants in chapter Biosignalling of Biochemistry
Answer» The CORRECT OPTION is (C) BRASSINOSTEROIDS Explanation: Brassinosteroids PREVENTS self-pollination.

Discussion

39.	Bacteria do not have which of the following receptors?(a) Adhesion receptors(b) Nuclear steroid receptors(c) Membrane proteins(d) GPCRThis question was posed to me during an internship interview.I want to ask this question from Signaling in Microorganisms and Plants in chapter Biosignalling of Biochemistry
Answer» CORRECT ANSWER is (b) Nuclear steroid receptors To EXPLAIN I WOULD say: Bacteria/plants do not have nuclear steroid receptors.

Discussion

40.	Which of the following is involved in phospho-tyrosine binding?(a) SH2(b) SH3(c) PTB(d) PHThis question was addressed to me in an online interview.Enquiry is from Multivalent Scaffold Proteins and Membrane Rafts in section Biosignalling of Biochemistry
Answer» Right choice is (a) SH2 The explanation is: SH3 is INVOLVED in PROLINE rich MOTIF binding.

Discussion

41.	PTB domains bind to ___________(a) Phosphorylated tyrosine(b) Phosphoryated threonine(c) Phosphorylated serine(d) Phosphorylated cysteineI had been asked this question in a job interview.I'd like to ask this question from Multivalent Scaffold Proteins and Membrane Rafts topic in portion Biosignalling of Biochemistry
Answer» The CORRECT ANSWER is (a) Phosphorylated tyrosine Explanation: Phosphotyrosine BINDING DOMAIN BINDS to phosphotyrosine.

Discussion

42.	Which second messenger signals the release of Ca^+2 from endoplasmic reticulum?(a) IP3(b) 1, 2 diacyl glycerol(c) cAMP(d) cGMPI have been asked this question in class test.My enquiry is from G Protein in section Biosignalling of Biochemistry
Answer» Correct answer is (a) IP3 Easiest explanation: IP3 BINDS to the RECEPTOR present on endoplasmic RETICULUM causing it to release calcium IONS.

Discussion

43.	Which of the following is a short-lived messenger that acts by stimulating a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG?(a) NO(b) NO2(c) NO3^–(d) N2OThis question was posed to me in an interview.This key question is from Receptor Enzymes topic in chapter Biosignalling of Biochemistry
Answer» Right ANSWER is (a) NO To EXPLAIN I would say: NO is a short-lived MESSENGER that acts by STIMULATING a soluble guanylyl cyclase, raising [cGMP] and stimulating PKG.

Discussion

44.	Voltage regulation means ____________(a) Na^+/K^+ pumps controls potential(b) Unless the voltage is regular gates will not respond(c) Oscilloscope only can control potential(d) With changes in the membrane potential voltage gated ion channels open and closeThe question was posed to me in a job interview.My question is based upon Gated Ion Channels topic in section Biosignalling of Biochemistry
Answer» Right option is (d) With CHANGES in the membrane POTENTIAL VOLTAGE gated ion channels open and close Explanation: With changes in the membrane potential voltage gated ion channels open and close, this is regulation of voltage.

Discussion

45.	The characteristic of malignant other than a benign tumor is?(a) Undergoes metastasis(b) Develops blood supply(c) Cell divides an unlimited number of times(d) Grows without needing a growth signalThis question was posed to me during an interview.I'd like to ask this question from Oncogenes, Tumor Suppressor Genes and Programmed Cell Death in section Biosignalling of Biochemistry
Answer» Right ANSWER is (a) Undergoes metastasis To explain: Only malignant TUMOR INVOLVES migration of CANCEROUS cells from the SITE of origin to other areas.

Discussion

46.	The characteristic of malignant other than a benign tumor is?(a) Undergoes metastasis(b) Develops blood supply(c) Cell divides an unlimited number of times(d) Grows without needing a growth signalI have been asked this question in an internship interview.This intriguing question comes from Oncogenes, Tumor Suppressor Genes and Programmed Cell Death in portion Biosignalling of Biochemistry
Answer»

Discussion

47.	At the end of each phase of cell cycle cyclins activating Cdks in that phase are inactivated irreversibly by _____________(a) Multiple phosphorylations(b) De-phosphorylation(c) Ubiquitinylation(d) Destabilizing by proteolysis in a proteosomeI got this question in homework.This intriguing question comes from Regulation of the Cell Cycle by Protein Kinases topic in chapter Biosignalling of Biochemistry
Answer» RIGHT option is (d) DESTABILIZING by proteolysis in a proteosome The explanation: At the END of each phase of cell cycle, cyclins are inactivated irreversibly by destabilizing by proteolysis in a proteasome.

Discussion

48.	What is Ubiquitin?(a) Protein kinase(b) Protease(c) Component of the electron transport system(d) Protein that tags another protein for proteolysisI had been asked this question during an internship interview.The doubt is from Regulation of the Cell Cycle by Protein Kinases topic in division Biosignalling of Biochemistry
Answer» Right option is (d) Protein that tags ANOTHER protein for proteolysis To explain: UBIQUITIN BINDS to a SUBSTRATE protein resulting in their degradation.

Discussion

49.	Which is an example of negative regulator?(a) CAP(b) Lac 1 gene(c) Nuclear receptors(d) Phosphorylated STAT proteinsI had been asked this question in final exam.My doubt stems from Regulation of Transcription by Steroid Hormones topic in division Biosignalling of Biochemistry
Answer» Right answer is (B) Lac 1 gene Best explanation: CAP, Nuclear receptors and Phosphorylated STAT PROTEINS are POSITIVE regulators.

Discussion

50.	In cholera there is uncontrolled secretion of _________(a) Na^+ and H2O(b) K^+ and H2O(c) Ca^+2 and H2O(d) Mg^+2 and H2OI got this question during an interview.The origin of the question is Sensory Transduction in Vision, Olfaction and Gustation in portion Biosignalling of Biochemistry
Answer» RIGHT OPTION is (a) Na^+ and H2O Explanation: There is an uncontrolled secretion of Na^+ and H2O in the INTESTINE.

Discussion

Explore topic-wise InterviewSolutions in .

A factor involved in regulating the fate of stem cells in plant development is _________(a) Adrenaline(b) Epinephrine(c) Thyroid stimulating hormone(d) CLV1The question was asked in examination.Question is from Signaling in Microorganisms and Plants topic in division Biosignalling of Biochemistry

A hormone or ligand can be considered as ___________(a) First messenger(b) Second messenger(c) Third messenger(d) Fourth messengerThe question was posed to me in semester exam.This is a very interesting question from G Protein in section Biosignalling of Biochemistry

What is the drug antagonist of estrogen?(a) Tanoxifen(b) Metformin(c) Glucophage(d) VictozaThe question was asked in a national level competition.The query is from Regulation of Transcription by Steroid Hormones topic in chapter Biosignalling of Biochemistry

ERF1is a _________(a) Translation terminating factor(b) Positive regulator(c) Translation promoting factor(d) Enzyme inhibitorI have been asked this question in exam.The question is from Signaling in Microorganisms and Plants topic in section Biosignalling of Biochemistry

In Arabidopsis flg22 binds to _________(a) FLS2(b) LPS(c) BAK1(d) MAPKThis question was posed to me by my college director while I was bunking the class.I want to ask this question from Signaling in Microorganisms and Plants topic in section Biosignalling of Biochemistry

Scaffold protein in insulin signal transduction ___________(a) KSR(b) IRS-1(c) MEKK1(d) AKAPI had been asked this question in exam.The query is from Multivalent Scaffold Proteins and Membrane Rafts topic in portion Biosignalling of Biochemistry

The receptor channels for which of the following are gated by extracellular ligands?(a) Glycine(b) IP3(c) cAMP(d) cGMPThe question was posed to me in unit test.The doubt is from Gated Ion Channels topic in chapter Biosignalling of Biochemistry

Receptor is removed from cell surface in _____________(a) Specificity(b) Amplification(c) Adaptation(d) IntegrationThis question was addressed to me in an interview for internship.My doubt stems from Molecular Mechanisms of Signal Transduction topic in section Biosignalling of Biochemistry

At which cell cycle checkpoint, cell cycle is halted if cell’s DNA is damaged?(a) G1 – S(b) S – G2(c) G2 – M(d) G0 – G1I got this question during an interview.Asked question is from Regulation of the Cell Cycle by Protein Kinases topic in division Biosignalling of Biochemistry

Which is an example of a positive regulator?(a) CAP(b) Lac 1 gene(c) Trp operon(d) Met operonThe question was posed to me during an interview.Asked question is from Regulation of Transcription by Steroid Hormones topic in portion Biosignalling of Biochemistry

Transcription factor in plants is _________(a) Serine(b) Threonine(c) WRKY22/29(d) LeucineThe question was asked during an online interview.I'd like to ask this question from Signaling in Microorganisms and Plants in section Biosignalling of Biochemistry

Which of the following serves as a neurotransmitter in adrenergic neurons?(a) Serotonin(b) Epinephrine(c) Dopamine(d) HistamineI had been asked this question in an internship interview.This question is from G Protein topic in division Biosignalling of Biochemistry

Which of the following is involved in phospho-tyrosine binding?(a) SH2(b) SH3(c) PTB(d) PHThis question was addressed to me in an online interview.Enquiry is from Multivalent Scaffold Proteins and Membrane Rafts in section Biosignalling of Biochemistry

Which second messenger signals the release of Ca^+2 from endoplasmic reticulum?(a) IP3(b) 1, 2 diacyl glycerol(c) cAMP(d) cGMPI have been asked this question in class test.My enquiry is from G Protein in section Biosignalling of Biochemistry

Which is an example of negative regulator?(a) CAP(b) Lac 1 gene(c) Nuclear receptors(d) Phosphorylated STAT proteinsI had been asked this question in final exam.My doubt stems from Regulation of Transcription by Steroid Hormones topic in division Biosignalling of Biochemistry

In cholera there is uncontrolled secretion of _________(a) Na^+ and H2O(b) K^+ and H2O(c) Ca^+2 and H2O(d) Mg^+2 and H2OI got this question during an interview.The origin of the question is Sensory Transduction in Vision, Olfaction and Gustation in portion Biosignalling of Biochemistry