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At the end of each phase of cell cycle cyclins activating Cdks in that phase are inactivated irreversibly by _____________(a) Multiple phosphorylations(b) De-phosphorylation(c) Ubiquitinylation(d) Destabilizing by proteolysis in a proteosomeI got this question in homework.This intriguing question comes from Regulation of the Cell Cycle by Protein Kinases topic in chapter Biosignalling of Biochemistry

Answer» RIGHT option is (d) DESTABILIZING by proteolysis in a proteosome

The explanation: At the END of each phase of cell cycle, cyclins are inactivated irreversibly by destabilizing by proteolysis in a proteasome.


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