InterviewSolution
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InterviewSolution
This section includes InterviewSolutions, each offering curated multiple-choice questions to sharpen your knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which is the first reaction of the pentose phosphate pathway?(a) Oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone(b) Oxidation of 6-phosphogluconate to ketopentose ribulose 5-phosphate(c) Reduction of 6-phosphoglucono-δ-lactone to glucose 6-phosphate(d) Reduction of ketopentose ribulose 5-phosphate to 6-phosphogluconateThe question was posed to me in a job interview.The above asked question is from Advanced Questions and Answers in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT answer is (a) OXIDATION of GLUCOSE 6-phosphate to 6-phosphoglucono-δ-lactone For EXPLANATION: The first reaction of the pentose phosphate PATHWAY is the oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone by glucose 6-phosphate dehydrogenase. |
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| 2. |
Which of the following increases gene expression as much as 200-fold?(a) TATA box(b) Insulator(c) Enhancer(d) CAAT boxI have been asked this question during an interview for a job.I'm obligated to ask this question of Regulation of Gene Expression in Prokaryotes-1 in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Correct option is (C) Enhancer |
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| 3. |
Lactose utilization by E. coli requires ____________(a) Lac-Z(b) Lac-A(c) Lac-Y(d) Lac-lThis question was posed to me by my school teacher while I was bunking the class.Query is from Principles of Gene Regulation topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT choice is (c) Lac-Y |
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| 4. |
Which of the following does not affect the stability of an α-helix?(a) Electrostatic repulsion(b) Bulkiness(c) Interaction between R groups spaced three residues apart(d) Occurrence of alanine and glycine residuesThe question was asked during a job interview.This key question is from Tricky Questions and Answers in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT CHOICE is (d) Occurrence of alanine and GLYCINE RESIDUES Best explanation: The occurrence of Proline and Glycine residues affects the STABILITY of an α-helix. |
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| 5. |
Which of the following is true?(a) The disulfide bridges formed by reduction of the sulfhydryl groups on cysteine stabilizes protein tertiary structure(b) The disulfide bridges formed by oxidation of the sulfhydryl groups on cysteine destabilize protein tertiary structure(c) The disulfide bridges formed by oxidation of the sulfhydryl groups on cysteine stabilizes protein tertiary structure(d) The disulfide bridges formed by reduction of the sulfhydryl groups on cysteine destabilize protein tertiary structureThis question was addressed to me during an online exam.Enquiry is from Tricky Questions and Answers topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct choice is (c) The disulfide bridges formed by oxidation of the sulfhydryl GROUPS on cysteine stabilizes protein tertiary STRUCTURE |
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| 6. |
Which of the following is not true about secondary protein structure?(a) The hydrophilic/hydrophobic character of amino acid residues is important to secondary structure(b) The ability of peptide bonds to form intramolecular hydrogen bonds is important to secondary structure(c) The alpha helix, beta pleated sheet and beta turns are examples of protein secondary structure(d) The steric influence of amino acid residues is important to secondary structureI got this question during an interview.My question is from Tough Questions and Answers in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT ANSWER is (a) The hydrophilic/hydrophobic CHARACTER of amino acid RESIDUES is important to secondary structure |
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| 7. |
Which of the following is false about fatty acids?(a) Melting point of fatty acids decreases with increase in the degree of saturation(b) Lipids in tissues that are subjected to cooling are more unsaturated(c) Naturally occurring unsaturated long-chain fatty acids are nearly Trans-configuration(d) The membrane lipids contain mostly unsaturated fatty acidsThe question was asked during a job interview.This intriguing question originated from Advanced Questions and Answers topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT ANSWER is (c) NATURALLY occurring unsaturated long-chain FATTY acids are nearly Trans-configuration |
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| 8. |
If pH of solution of NaOH is 12.0 the pH of H2SO4 solution of same molarity will be ____________(a) 2.0(b) 12.0(c) 1.7(d) 10.0387I got this question in an interview for internship.Question is from Tricky Questions and Answers topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right OPTION is (C) 1.7 |
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| 9. |
To which class of transcription factor do nuclear receptors belong?(a) Zinc finger proteins(b) Leucine zipper proteins(c) Helix-turn-helix proteins(d) Helix-loop-helix proteinsI had been asked this question by my college professor while I was bunking the class.My query is from Regulation of Gene Expression in Prokaryotes-1 in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT ANSWER is (a) Zinc finger proteins Easiest explanation: Nuclear receptors BELONG to the zinc finger MOTIF. |
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| 10. |
Which of the following are important for white blood cell recognition?(a) Glycosaminoglycans(b) Proteoglycans(c) Glycoproteins(d) GlycolipidsThis question was addressed to me in examination.The origin of the question is Tough Questions and Answers topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT answer is (c) Glycoproteins |
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| 11. |
The enzyme of E.coli is a nuclease that initiates the repair of double stranded DNA breaks by homologous recombination is?(a) DNA glycosylase(b) DNA ligase(c) DNA polymerase(d) RNA polymeraseThis question was posed to me in a national level competition.This key question is from Tough Questions and Answers topic in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct CHOICE is (a) DNA glycosylase |
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| 12. |
The lactose repressor is encoded by ____________(a) Lac-l(b) Lac-A(c) Lac-Y(d) Lac-ZThe question was asked in a national level competition.My question comes from Principles of Gene Regulation topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Correct OPTION is (a) Lac-l |
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| 13. |
Which of the following is abundantly found in collagen?(a) Glycine(b) Serine(c) Alanine(d) TryptophanI got this question in semester exam.I'm obligated to ask this question of Tough Questions and Answers topic in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right option is (a) Glycine |
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| 14. |
Which of the following statement is false?(a) Lysozyme has S-S linkage(b) Ribonuclease has S-S linkage(c) Heme group in cytochrome c is covalently linked to the protein on two sides(d) Ribonuclease has SH-SH linkageI had been asked this question in a job interview.Question is taken from Tough Questions and Answers topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT answer is (d) RIBONUCLEASE has SH-SH linkage |
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| 15. |
Which of the following serves as a bactericidal agent?(a) Ribonuclease(b) Lysozyme(c) Cytochrome c(d) MyoglobinI had been asked this question in an online interview.Origin of the question is Tough Questions and Answers in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT choice is (B) LYSOZYME Explanation: Lysozyme can LYSE, or DEGRADE, bacterial cell walls, so it serves as a bactericidal agent. |
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| 16. |
A structure that has hydrogen bonds between polypeptide chains arranged side by side is ____________(a) Primary structure(b) α-helix(c) β-pleated sheets(d) Tertiary structureThis question was posed to me by my college professor while I was bunking the class.My doubt is from Tough Questions and Answers topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT OPTION is (C) β-pleated sheets Explanation: A structure that has hydrogen bonds between polypeptide CHAINS ARRANGED side by side is β-pleated sheets. |
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| 17. |
Whose interaction with Lex-A facilitates the repressor’s self-cleavage reaction?(a) Rec-A(b) Rec-B(c) Rec-C(d) Rec-DThis question was posed to me in an internship interview.The above asked question is from Regulation of Gene Expression in Prokaryotes in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right ANSWER is (a) Rec-A |
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| 18. |
Which of the following about mRNA stability is not correct?(a) Regulation of mRNA stability is a way of regulating gene expression(b) Prokaryotic mRNAs have a half-life of only a few minutes(c) Histone mRNAs have especially long poly-A tails and are stable(d) It is thought that poly-A tails stabilize eukaryotic mRNAsThis question was posed to me in class test.This key question is from Regulation of Gene Expression in Prokaryotes-1 in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT option is (c) HISTONE mRNAs have especially long poly-A TAILS and are stable For EXPLANATION: Histone mRNAs lack poly-A tails so they are unstable. |
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| 19. |
The binding of ligands to many GPCRs leads to ____________(a) Decrease in concentration of second messengers(b) Increase in concentration of second messengers(c) Decrease in concentration of first messengers(d) Increase in concentration of first messengersThe question was asked during an interview for a job.Query is from Advanced Questions and Answers topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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| 20. |
Which of the following regulatory sequence allows transcription to continue?(a) Sequence 1(b) Sequence 2(c) Sequence 3(d) Sequence 4I have been asked this question in class test.The origin of the question is Regulation of Gene Expression in Prokaryotes topic in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Correct answer is (b) SEQUENCE 2 |
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| 21. |
Site directed mutagenesis facilitated research on ____________(a) Carbohydrates(b) Proteins(c) Lipids(d) FatsThe question was posed to me during a job interview.Question is taken from Advanced Questions and Answers topic in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT answer is (b) Proteins To ELABORATE: Site DIRECTED mutagenesis changes the amino acid sequence by altering DNA sequence of the CLONED gene. It facilitates research on proteins. |
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| 22. |
In 3° structure of proteins, folding and shaping is done by ____________(a) Hydrophobic interactions(b) Polar interactions(c) Hydrogen bonding(d) None of the mentionedThis question was addressed to me in an internship interview.Asked question is from Tricky Questions and Answers topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right choice is (a) Hydrophobic interactions |
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| 23. |
Which of the following is not the classified form of conjugated proteins?(a) Lipoproteins(b) Glycoproteins(c) Metalloproteins(d) Complete proteinsI have been asked this question by my college director while I was bunking the class.My question comes from Tricky Questions and Answers in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT option is (d) Complete PROTEINS |
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| 24. |
Which of the following takes place when tryptophan levels are low?(a) Ribosomes quickly translates sequence 1(b) Sequence 2 is blocked before sequence 3 is transcribed(c) Ribosomes pauses at the Try codons in sequence 1(d) Attenuation at the attenuator structure formed by sequences of 3 and 4The question was asked by my school principal while I was bunking the class.This interesting question is from Regulation of Gene Expression in Prokaryotes in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Correct answer is (C) Ribosomes pauses at the Try codons in sequence 1 |
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| 25. |
Which of the following catalyzes the cutting of PIP2 into 2 moles of IP3 and diacylglycerol in cell signaling?(a) Phosphokinase C(b) Phospholipase C(c) Lipokinase(d) Phosphodiesterase CThis question was posed to me during an internship interview.The origin of the question is Advanced Questions and Answers in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right CHOICE is (B) PHOSPHOLIPASE C |
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| 26. |
Which of the following is a hydroxyl fatty acid?(a) Linoleic acid(b) Palmitic acid(c) Linolenic acid(d) Cerebronic acidThe question was posed to me in class test.The question is from Advanced Questions and Answers topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct OPTION is (d) Cerebronic acid |
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| 27. |
Which of the statements is false about multiple sequence alignment?(a) Both protein and nucleic acid secondary structures can be used(b) More useful in RNA(c) These alignments can be made more accurate by the inclusion of secondary structure information(d) A significant increase in accuracyThe question was posed to me in final exam.This intriguing question originated from Tough Questions and Answers in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT option is (b) More useful in RNA Easy explanation: LESS useful in RNA. This is because base PAIRING is highly CONSERVED than sequence. |
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| 28. |
What trend does the reactivity of group II elements follow with water?(a) Increases down the group(b) Decreases down the group(c) Does not follow any particular trend(d) No reactionI have been asked this question in quiz.I need to ask this question from Tricky Questions and Answers topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT option is (a) Increases down the group Explanation: As we descend down the group, LOSING of ELECTRONS from the outer orbit of an ATOM becomes EASY. |
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| 29. |
Which of the following are included in the types of glycolipids?(a) N-acetylgalactosamine(b) N-acetylglucosamine(c) Xylose(d) CerebrosidesI have been asked this question in homework.I'd like to ask this question from Advanced Questions and Answers in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Correct OPTION is (d) Cerebrosides |
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| 30. |
Which of the following takes place when tryptophan levels are high?(a) Attenuation at the attenuator structure formed by sequences of 3 and 4(b) Ribosomes pauses at the Try codons in sequence 1(c) Formation of paired structure between 2 and 3 sequences prevents attenuation(d) 2:3 structures, unlike the 3:4 attenuator, does not prevent transcriptionThis question was addressed to me by my school principal while I was bunking the class.Query is from Regulation of Gene Expression in Prokaryotes topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Correct option is (a) Attenuation at the attenuator structure FORMED by SEQUENCES of 3 and 4 |
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| 31. |
RNAi stands for ____________(a) RNA inducer(b) RNA interference(c) RNA intron(d) RNA insertionThe question was asked in an interview.This key question is from Regulation of Gene Expression in Prokaryotes-1 topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct answer is (B) RNA interference |
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| 32. |
Where does a repressor bind an operon?(a) Operator(b) Promoter(c) Inducer(d) Catabolite activator siteThe question was asked in semester exam.My question is taken from Principles of Gene Regulation topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT choice is (a) OPERATOR To explain I WOULD say: REPRESSOR binds an operon at the operator. |
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| 33. |
Attenuator sequences base-pair to form a stem-and-loop structure rich in ____________(a) A = T(b) G ≡ C(c) A = C(d) G = CThe question was asked in exam.This key question is from Regulation of Gene Expression in Prokaryotes topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right CHOICE is (b) G ≡ C |
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| 34. |
Which of the following statements about lac operon in e.coli is true?(a) Promoter is the binding site for the lac repressor(b) Operon is only switched on in the absence of lactose in the growth medium(c) β-galactosidase is only produced in large quantities when the lac repressor is bound to the operator(d) Lac operon mRNA is a polycistronic mRNAThe question was asked in quiz.This intriguing question originated from Regulation of Gene Expression in Prokaryotes-1 topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct choice is (d) LAC OPERON mRNA is a polycistronic mRNA |
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| 35. |
Which of the following glycoprotein functions as a lubricant and protective agent?(a) Collagens(b) Mucins(c) Transferrins(d) ImmunoglobulinsI got this question in examination.The query is from Advanced Questions and Answers in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The CORRECT OPTION is (b) MUCINS |
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| 36. |
Which of the following is a hypertonic solution?(a) Oceans(b) Freshwater habitats(c) 0.45% sodium chloride(d) Red blood cells placed in fresh waterThis question was addressed to me in an online quiz.Question is from Tricky Questions and Answers topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right option is (a) OCEANS |
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| 37. |
Which of the following is first determined as oligomer?(a) Myoglobin(b) Collagen(c) Keratin(d) HemoglobinThe question was asked in an interview for internship.My question is taken from Tough Questions and Answers topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right option is (d) Hemoglobin |
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| 38. |
Trp repressor is a ____________(a) Homodimer(b) Homotrimer(c) Heterodimer(d) HeterotrimerI had been asked this question during an online interview.I'd like to ask this question from Regulation of Gene Expression in Prokaryotes topic in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right choice is (a) Homodimer |
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| 39. |
Which out of the following is not an example of an inducible operon?(a) Lactose operon(b) Galactose operon(c) Maltose operon(d) Tryptophan operonThe question was asked in examination.Question is from Principles of Gene Regulation topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT OPTION is (d) Tryptophan operon The EXPLANATION is: Lactose operon, galactose operon and maltose operon are EXAMPLES of the INDUCIBLE operon. |
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| 40. |
Which of the following is not required for the expression of genes in the lactose operon?(a) lacl gene product(b) cAMP(c) Allolactose(d) Adenylate cyclaseI had been asked this question in a job interview.My question is taken from Principles of Gene Regulation in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» RIGHT CHOICE is (a) lacl gene product The explanation is: cAMP, allolactose and adenylate CYCLASE are REQUIRED for the EXPRESSION of genes in the lactose operon. |
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| 41. |
If lactose and glucose are provided in the growth medium of a culture of E. coli ____________(a) Lactose operon is not transcribed(b) Lactose metabolism is favored(c) Both lactose and glucose are metabolized at same rate(d) Adenylate cyclase is activatedI have been asked this question in a national level competition.This interesting question is from Principles of Gene Regulation topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT choice is (a) Lactose operon is not TRANSCRIBED To explain I would SAY: If lactose and GLUCOSE are provided in the growth medium of a culture of E. coli lactose operon is not transcribed. |
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| 42. |
Which of the following is not an example of housekeeping genes?(a) RNA polymerase(b) r-RNA genes(c) Beta galactosidase(d) Enzymes required for basic metabolic pathways common to most cellsThis question was addressed to me during an interview.My doubt stems from Principles of Gene Regulation topic in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right CHOICE is (c) Beta galactosidase |
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| 43. |
Oxidation of 3 molecules of glucose by pentose phosphate pathway results in the production of ____________(a) 3 molecules of pentose, 6 molecules of NADPH and 3 molecules of CO2(b) 4 molecules of pentose, 6 molecules of NADPH and 3 molecules of CO2(c) 4 molecules of pentose, 3 molecules of NADPH and 3 molecules of CO2(d) 3 molecules of pentose, 4 molecules of NADPH and 3 molecules of CO2The question was posed to me by my school principal while I was bunking the class.My question comes from Advanced Questions and Answers in chapter Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT option is (a) 3 molecules of pentose, 6 molecules of NADPH and 3 molecules of CO2 To EXPLAIN: Glucose 6-phosphate + 2NADP^+ + H2O → ribose 5-phosphate + CO2 + 2NADPH + 2H^+. |
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| 44. |
Which of the following enzyme is secreted by the pancreas?(a) Ribonuclease(b) Lysozyme(c) Cytochrome c(d) MyoglobinI have been asked this question in final exam.My doubt is from Tough Questions and Answers topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct CHOICE is (a) Ribonuclease |
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| 45. |
Which of the following is the most appropriate definition of an operator?(a) A non-coding, regulatory DNA sequence that is bound by RNA polymerase(b) A non-coding, regulatory DNA sequence that is bound by a repressor protein(c) A DNA-binding protein that regulates gene expression(d) A cluster of genes that are regulated by a single promoterThe question was posed to me during an interview.The query is from Regulation of Gene Expression in Prokaryotes-1 in portion Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT choice is (b) A non-coding, regulatory DNA sequence that is BOUND by a repressor protein Easy explanation: A repressor BINDS to the OPERATOR. |
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| 46. |
What does it mean when we say that water acts as a “heat buffer”?(a) It keeps the temperature of an organism relatively constant as the temperature of the surroundings fluctuates(b) It increases the temperature of an organism as the temperature of the surroundings increases(c) It decreases the temperature of an organism as the temperature of the surroundings increases(d) It increases the temperature of an organism as the temperature of the surroundings decreasesI got this question by my school principal while I was bunking the class.The query is from Tricky Questions and Answers topic in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right CHOICE is (a) It keeps the TEMPERATURE of an ORGANISM relatively constant as the temperature of the surroundings fluctuates |
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| 47. |
Which of the following encodes recombinase?(a) fliC(b) fljB(c) hin(d) fljAI have been asked this question by my school teacher while I was bunking the class.My query is from Regulation of Gene Expression in Prokaryotes in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right CHOICE is (c) hin |
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| 48. |
Formation of the attenuator stem-and-loop structure depends on the events that occur during translation of ____________(a) Regulatory sequence 1(b) Regulatory sequence 2(c) Regulatory sequence 3(d) Regulatory sequence 4I have been asked this question in final exam.I want to ask this question from Regulation of Gene Expression in Prokaryotes topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» Right answer is (a) Regulatory sequence 1 |
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| 49. |
Which of the following statements is not correct?(a) Bacteria possess only one type of RNA polymerase(b) Attenuation is a regulatory process used by bacteria to control the initiation of transcription(c) Repressor binds to operator(d) Bacterial genes are polycistronicI had been asked this question in examination.This key question is from Regulation of Gene Expression in Prokaryotes-1 topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» CORRECT CHOICE is (b) Attenuation is a regulatory PROCESS used by bacteria to CONTROL the initiation of transcription Explanation: Attenuation results in PREMATURE termination of transcription. |
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| 50. |
Lac repressor dissociates from its operator when the repressor binds to ____________(a) Heat shock module(b) Promoter(c) Inducer(d) Catabolite activator siteI have been asked this question in final exam.My question is from Principles of Gene Regulation topic in section Regulation of Gene Expression and Miscellaneous of Biochemistry |
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Answer» The correct option is (C) Inducer |
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