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Which is the first reaction of the pentose phosphate pathway?(a) Oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone(b) Oxidation of 6-phosphogluconate to ketopentose ribulose 5-phosphate(c) Reduction of 6-phosphoglucono-δ-lactone to glucose 6-phosphate(d) Reduction of ketopentose ribulose 5-phosphate to 6-phosphogluconateThe question was posed to me in a job interview.The above asked question is from Advanced Questions and Answers in division Regulation of Gene Expression and Miscellaneous of Biochemistry |
Answer» RIGHT answer is (a) OXIDATION of GLUCOSE 6-phosphate to 6-phosphoglucono-δ-lactone For EXPLANATION: The first reaction of the pentose phosphate PATHWAY is the oxidation of glucose 6-phosphate to 6-phosphoglucono-δ-lactone by glucose 6-phosphate dehydrogenase. |
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