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Which of the following catalyzes the cutting of PIP2 into 2 moles of IP3 and diacylglycerol in cell signaling?(a) Phosphokinase C(b) Phospholipase C(c) Lipokinase(d) Phosphodiesterase CThis question was posed to me during an internship interview.The origin of the question is Advanced Questions and Answers in section Regulation of Gene Expression and Miscellaneous of Biochemistry

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Right CHOICE is (B) PHOSPHOLIPASE C

Best explanation: PLC also named phospholipase grabs onto PIP2 and cuts it into diacylglycerol and IP3.



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