A length and distance that gives the highest overall probability may then be determined. Such alignments are initially found using ________(a) a particular scoring matrix only(b) an alignment algorithm only(c) an alignment algorithm and a particular scoring matrix(d) dot methodThe question was asked during an interview for a job.I want to ask this question from Bayesian Statistics in division Sequence Alignment of Bioinformatics

A length and distance that gives the highest overall probability may t

1.	A length and distance that gives the highest overall probability may then be determined. Such alignments are initially found using ________(a) a particular scoring matrix only(b) an alignment algorithm only(c) an alignment algorithm and a particular scoring matrix(d) dot methodThe question was asked during an interview for a job.I want to ask this question from Bayesian Statistics in division Sequence Alignment of Bioinformatics
Answer» The CORRECT answer is (c) an alignment algorithm and a particular scoring matrix Explanation: ANALYSIS of the yeast and C. elegans genomes for such repeats has underscored the importance of using a range of DNA scoring MATRICES such as PAM1 to PAM120 if most repeats are to be found. The application of the above Bayesian analysis allows a DETERMINATION of the probability distributions as a function of both LENGTH of the repeated region and evolutionary distance.

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