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A non-disjunction in the 1^st phase of meiosis will lead to ______________(a) Monosomy(b) Nullysomy(c) Disomy(d) TrtrasomyThis question was addressed to me at a job interview.I'd like to ask this question from Chromosomal Abnormalities : Aneuploidy topic in portion Chromosomal Basis of Inheritance of Cytogenetics

Answer»

The correct option is (b) Nullysomy

Best explanation: Nullysomy in chromosome is a LOSS of 2 CHROMOSOMES i.e. loss of a CHROMOSOMAL pair. This can RESULT from passing of both homologous chromosomes to the same POLE during meiosis 1- this pole will produce trisomic gametes while the counterpart will produce nullisomic gametes.



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