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By whom and when were the Bayesian methods applied first?(a) Smith-Waterman, 1981(b) Agarwal and States, 1996(c) Smith-Waterman, 1996(d) Agarwal and States, 1981This question was posed to me in final exam.This interesting question is from Bayesian Statistics topic in portion Sequence Alignment of Bioinformatics

Answer»

Right choice is (b) Agarwal and States, 1996

The best I can explain: Agarwal and States, in1996, have applied BAYESIAN methods to provide the best estimate of the evolutionary distance between TWO DNA sequences. For example, sequences of the same LENGTH that have a certain LEVEL of mismatches.



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