Consider this sequence A—O—B —C—D—E—F, be a DNA sequence where O is the centromere. Which of the following will be a pericentric inversion?(a) A—O—B—D—E—F(b) B—O—A—D—E—F(c) D—B—O—A—E—F(d) A—O—E—D—B—FI have been asked this question in my homework.This intriguing question comes from Chromosomal Abnormality : Inversion topic in division Chromosomal Basis of Inheritance of Cytogenetics

Consider this sequence A—O—B —C—D—E—F, be a DNA sequence w

1.	Consider this sequence A—O—B —C—D—E—F, be a DNA sequence where O is the centromere. Which of the following will be a pericentric inversion?(a) A—O—B—D—E—F(b) B—O—A—D—E—F(c) D—B—O—A—E—F(d) A—O—E—D—B—FI have been asked this question in my homework.This intriguing question comes from Chromosomal Abnormality : Inversion topic in division Chromosomal Basis of Inheritance of Cytogenetics
Answer» Right choice is (d) A—O—E—D—B—F Easy explanation: PERICENTRIC inversion is the inversion that doesn’t involve the CENTROMERE. Here in OPTION A there is no change at all, option B and C are including the centromere. Only option D doesn’t involve the centromere in the inverted SEQUENCE, so it is pericentric.

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