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Coregenes is a web-based program that determines a ________ set of genes based on comparison of ________ small genomes.(a) vast, four(b) core, fifteen(c) core, four(d) vast, fifteenThe question was posed to me by my college director while I was bunking the class.This interesting question is from Comparative Genomics in section Genome Mapping, Assembly and Comparison of Bioinformatics

Answer»

Correct choice is (c) core, four

For explanation: The user supplies NCBI accession numbers for the genomes of INTEREST. The PROGRAM performs an iterative BLAST comparison to find orthologous genes by using one GENOME as a reference and another as a QUERY. This pairwise comparison is performed for all four genomes. As a result, the COMMON genes are compiled as a core set of genes from the genomes.



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