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Deletion of a region led to over expression of a gene X. What do you conclude from this observation?(a) Part of gene X is mutated(b) Promoter of gene X is deleted(c) Regulator of gene X is deleted(d) No effect on gene X or its regulatorsI have been asked this question in an international level competition.Question is from Chromosomal Abnormalities : Deletion topic in chapter Chromosomal Basis of Inheritance of Cytogenetics

Answer»

The correct choice is (c) Regulator of gene X is deleted

Explanation: In this case over EXPRESSION of gene X is due to deletion of some negative regulator like OPERON, insulator, silencer ETC.



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