In ab initio methods for RNA structure prediction, the prediction results from RNAfold are not always guaranteed to be better than those predicted by Mfold.(a) True(b) FalseI got this question in an interview.I would like to ask this question from Comparative Approach topic in section RNA Structure Prediction of Bioinformatics

In ab initio methods for RNA structure prediction, the prediction resu

1.	In ab initio methods for RNA structure prediction, the prediction results from RNAfold are not always guaranteed to be better than those predicted by Mfold.(a) True(b) FalseI got this question in an interview.I would like to ask this question from Comparative Approach topic in section RNA Structure Prediction of Bioinformatics
Answer» The correct option is (a) True To EXPLAIN I would say: Because of the much larger NUMBER of secondary structures to be computed, a more simplified energy rule has to be used to INCREASE computational SPEED. Thus, the PREDICTION results are not always guaranteed to be better than those predicted by Mfold.

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