In ab initio methods, free energy can be calculated based on parameters empirically derived for small molecules.(a) True(b) FalseThis question was addressed to me in final exam.My query is from RNA Secondary Structure Prediction Methods in section RNA Structure Prediction of Bioinformatics

In ab initio methods, free energy can be calculated based on parameter

1.	In ab initio methods, free energy can be calculated based on parameters empirically derived for small molecules.(a) True(b) FalseThis question was addressed to me in final exam.My query is from RNA Secondary Structure Prediction Methods in section RNA Structure Prediction of Bioinformatics
Answer» RIGHT ANSWER is (a) True Best explanation: G–C base pairs are more stable than A–U base pairs, which are more stable than G–U base pairs. It is also known that base-pair FORMATION is not an INDEPENDENT event.

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