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In dynamic programming, in ab initio methods, Often ________ base pairing and energy terms of the base pairing _____ incorporated into the scoring process.(a) G-C, are(b) G–U, are not(c) G–U, are also(d) G-C, are notThis question was posed to me during a job interview.My query is from Ab Initio Approach in section RNA Structure Prediction of Bioinformatics

Answer»

Right answer is (C) G–U, are also

The best explanation: Although the traditional structure COMPRISES of A–U and G–C base pairs, G-U base pairing is incorporated into the scoring process. A path with the maximal score within a scoring MATRIX after taking into account the entire sequence information represents the most PROBABLE secondary structure FORM.



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