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In dynamic programming, in ab initio methods, the use of a dot plot can be effective in finding a ____ secondary structure in a ________ molecule.(a) multiple, large(b) single, large(c) single, small(d) multiple, smallI got this question in a national level competition.My question is taken from Ab Initio Approach in chapter RNA Structure Prediction of Bioinformatics

Answer»

The CORRECT answer is (c) SINGLE, small

The explanation: Mostly, The use of a DOT plot can be effective in finding a single secondary structure in a small Molecule. However, if a LARGE molecule contains MULTIPLE secondary structure segments, choosing a combination that is energetically most stable among a large number of possibilities can be a daunting task.



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