In Genome-wide prediction of protein functions by a combinatorial method– Each point represents a protein, and branches between proteins indicate a relationship by one of several criteria indicated in the legend.(a) True(b) FalseThe question was asked in class test.My question is taken from Prediction of Gene Function Based on a Composite Analysis topic in division Genome Analysis of Bioinformatics

In Genome-wide prediction of protein functions by a combinatorial meth

1.	In Genome-wide prediction of protein functions by a combinatorial method– Each point represents a protein, and branches between proteins indicate a relationship by one of several criteria indicated in the legend.(a) True(b) FalseThe question was asked in class test.My question is taken from Prediction of Gene Function Based on a Composite Analysis topic in division Genome Analysis of Bioinformatics
Answer» Correct choice is (a) True Explanation: BRANCH lengths are shorter for closely RELATED proteins and thicker when two or more prediction methods indicate a relationship. The links are based on experimental data, proteins WHOSE homologs are known to operate sequentially in metabolic pathways, proteins that evolved in a correlated FASHION as evidenced by presence in fully sequenced genomes, proteins whose homologs are fused into a single protein in another organism, and proteins whose mRNA expression PROFILES are similar under a range of cellular and environmental conditions.

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