Related InterviewSolutions

• A genome database may also be interfaced with other types of data, such as clinical data.(a) True(b) FalseI got this question in homework.The doubt is from Prediction of Gene Function Based on a Composite Analysis topic in division Genome Analysis of Bioinformatics
• Once a set of genes that are co-regulated has been found, the promoter regions of these genes may be analyzed for conserved patterns that represent sites of interaction with specific transcription factors.(a) True(b) FalseThis question was addressed to me in quiz.My question is from Global Gene Regulation topic in division Genome Analysis of Bioinformatics
• SVMs (Support vector machines) are a binary classification method to discriminate one set of data points from another.(a) True(b) FalseI have been asked this question during an interview.This key question is from Global Gene Regulation in section Genome Analysis of Bioinformatics
• Two species that have recently diverged from a common ancestor might be expected to have a ________ set of genes and ________ chromosomes with these genes positioned along the chromosomes in the same order.(a) distinct, similar(b) similar, distinct(c) similar, dissimilar(d) similar, similarI had been asked this question in examination.The origin of the question is Functional Classification of Genes in chapter Genome Analysis of Bioinformatics
• Which of the given statements is incorrect about Microarray (or microchip) analysis?(a) It is a new technology in which all of the genes of an organism are represented by oligonucleotide sequences spread out in an 80 x 80 array on microscope slides(b) The oligonucleotide sequences cannot be synthesized directly on the slide(c) The oligonucleotides are collectively hybridized to a labeled cDNA library prepared by reverse-transcribing mRNA from cells(d) The amount of label binding to each oligonucleotide spot reflects the amount of mRNA in the cellI had been asked this question during an interview.Question is from Global Gene Regulation in division Genome Analysis of Bioinformatics
• Which of the given statement is incorrect regarding MAGPIE?(a) It analyzes the genome using a set of automated processes(b) It is designed for high-throughput genome sequence analysis(c) It is unable to locate potential promoters(d) It automatically annotates genomic sequence data and maintains a daily up-to-date record in response to user queries about one or more genomesThe question was posed to me in an interview.My question is from Functional Classification of Genes in section Genome Analysis of Bioinformatics
• When two proteins share a considerable degree of sequence identity throughout the sequence alignment, they are least likely to share the same function.(a) True(b) FalseI had been asked this question in an online quiz.The doubt is from Prediction of Gene Function Based on a Composite Analysis topic in division Genome Analysis of Bioinformatics
• In cluster analysis of microarray data– For n genes, the process is repeated ________ times until a single element remains.(a) n^2(b) n(c) n^-1(d) n^-4The question was posed to me by my college professor while I was bunking the class.The doubt is from Global Gene Regulation topic in chapter Genome Analysis of Bioinformatics
• Which of the given statement is incorrect?(a) Paralogous sequences, frequently are found to have dissimilar functions(b) An early classification scheme for eight related groups of E. coli genes included categories for enzymes, transport elements(c) An early classification scheme for eight related groups of E. coli genes included categories for regulators, membranes, structural elements, protein factors, leader peptides, and carriers(d) Ninety percent of E. coli genes related by significant sequence similarity fell into these same broad categoriesThis question was posed to me in an internship interview.My question is from Functional Classification of Genes in chapter Genome Analysis of Bioinformatics
• Which of the given statement is incorrect about the Chromosomal Rearrangements?(a) Comparison of the number of rearrangements in a given period of evolutionary history may vary significantly from one organism to the next(b) If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, there is an increased probability of an ortholog of B also occurring in the other organism(c) If gene A has a neighboring gene B, then if an ortholog of A occurs in another genome, the B ortholog is more likely to be a neighbor of the A ortholog of the genome of the second species if the two species are more divergent(d) In general, the order of orthologs is not well conserved in prokaryotes when the genomes have diverged sufficiently that the orthologs have < 50% identityI have been asked this question in a national level competition.Question is from Functional Classification of Genes in chapter Genome Analysis of Bioinformatics