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In the sulfation process, what is the name of the coenzyme formed in the 1st step?(a) 3’-phosphoadenosine-5’-phosphosulfate(b) Adenosine triphosphate(c) Adenosine-5’-phosphosulfate(d) Uridine-5’-diphosphate-alpha-D-glucuronic acidThis question was addressed to me in final exam.My query is from Drugs Biotransformation in section Biotransformation of Drugs of Drug Biotechnology

Answer»

Correct ANSWER is (a) 3’-phosphoadenosine-5’-phosphosulfate

Explanation: In the 1st step of sulphation, synthesis of an ACTIVE coenzyme takes place. The coenzyme name is 3’-phosphoadenosine-5’-phosphosulfate. This coenzyme acts as a DONOR of SULFATE to the substrate.



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