In the zinc finger, which residues in this sequence motif form ligands to a zinc ion?(a) Cysteine and histidine(b) Cysteine and arginine(c) Histidine and proline(d) Histidine and arginineThe question was asked during an internship interview.This is a very interesting question from Protein Motifs and Domain Prediction in chapter Sequence Alignment of Bioinformatics

In the zinc finger, which residues in this sequence motif form ligands

1.	In the zinc finger, which residues in this sequence motif form ligands to a zinc ion?(a) Cysteine and histidine(b) Cysteine and arginine(c) Histidine and proline(d) Histidine and arginineThe question was asked during an internship interview.This is a very interesting question from Protein Motifs and Domain Prediction in chapter Sequence Alignment of Bioinformatics
Answer» Right option is (a) Cysteine and histidine To explain: In the zinc FINGER, which is found in a widely VARYING FAMILY of DNA-binding proteins, cysteine and histidine residues in this SEQUENCE motif form ligands to a zinc ion whose coordination is essential to stabilize the TERTIARY structure.

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