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Long pericentric inversions generally don’t act as cross over suppressors. Why?(a) Long stretches of DNA recombination not recognized(b) Mechanism is different for short and long inversions(c) Two events of crossing over take place(d) Cross over product in this is viableI had been asked this question in my homework.I'd like to ask this question from Chromosomal Abnormality : Inversion topic in division Chromosomal Basis of Inheritance of Cytogenetics

Answer»

The correct option is (c) Two events of crossing over take place

The explanation: Longer stretches of inversion favour formation of Double Crossover, then the DNA are resolved normally between all 4 meiotic products and no dicentric CHROMOSOME is formed. Thus, Long pericentric inversion GENERALLY don’t act as cross over suppressors.



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