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Motifs that can form α/β horseshoes conformation are rich with which protein residue?(a) Proline(b) Arginine(c) Valine(d) LeucineThe question was posed to me in quiz.I need to ask this question from Protein Motifs and Domain Prediction topic in portion Sequence Alignment of Bioinformatics

Answer» RIGHT answer is (d) Leucine

To elaborate: Specific pattern of Leucine residues, strands form a curved sheet with helices on the outside. Leucine-rich repeats (LRRs) are 20-29-residue SEQUENCE motifs present in a number of proteins with diverse functions. The PRIMARY function of these motifs APPEARS to be to provide a versatile STRUCTURAL framework for the formation of protein-protein interactions.


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