I have had this problem before. I WENT into a dell forum for help and got it. Since then I was cleaning up OLD files and PROGRAMS and now I get that message. D:\is not accessible. It was my understanding that when I reinstalled Windows sometime back that the computer did not recognize the CD ROM. I downloaded the suggestion they gave me and it worked fine until I got clean happy trying to get the computer to run faster.

I spent much time with Dell Support YESTERDAY but to no avail. They insist I need a new driver. Device Manager said it works properly. I did the delete upper & lower filters, didn't help. I can run audio CD's but none of the CD's that came with the computer. It always tells to insert a disk into drive D. I have uninstalled and reinstalled and update driver,etc.

I have Windows XP service pack 2

Any suggestions??

You don't need drivers for your CD ROM.
Did you try to uninstall it through Device Manager, and restart your computer, so Windows can find it again?If it RUNS audio CD's but will not read a data CD the drive may be on it's last legs...
They are not that expensive to replace now and have a lifespan of an average of 3 years or so...
Your mileage may vary.Trying lens cleaning CD, could be another option. Cleaning those data CDs, as well. Will those data CDs load on another computer?Try those other options before you decide to reinstall.