I cannot get any computer mouse to work with my computer. I've tried both USB, and Ps/2 ported mouses and neither will work. WELL to some point they do but what happens it they work fine for 10-15 seconds and then they start LAGGING and then freeze up permanently, which can only be remedied by a complete restart. Virus Scans, Defrags, and System Restores have come up with nothing. Is there anything I can do to fix this? One solution I have found is to completely wipe the hard-drive and then reinstalling your OS which I have done but to no avail the problem persists.

I am using a Compaq Presario Desktop. (don't know what the model is)

2Ghz Athlon 64 processor
1.5Gb RAM
110Gb? hard drive
500watt Power Source
EVGA 9800GT GPU
>I'm sure there are some other things I cannot remember at the moment.
All in all its been a decent setup until this problem reared it ugly head.
As mentioned before I have tried several different mice ranging from USB to Ps/2 ports. None will work.
I previously had Windows Vista 32bit loaded on and have SINCE blanked my hard drive to see if that worked, but it did not. I am using a Sabayon Linux Live CD to get on the computer right now and the standard trackball mouse that CAME with the computer originally is working okay for the moment, but I would like to be able to get my wireless optical mouse to work as the trackball mouse is simply junk.

Is there anything I can do to resolve this issue?
Did you install you chipset driver?I haven't but now its kind of late as I don't have an operating system installed, and I also don't know where to find the chipset drivers for my computer, and I have AMD Sempron not Athlon my mistake. I'm in the process of installing Sabayon Linux and after that I will find the appropriate chipset drivers, and see if that resolves the issue.

I've finished installing Linux and the mouse was still having problems so I 'gently' chucked it at the ground and it started working for the time anyway. Will update again if the problem comes back. I have a feeling that this was probably just a COINCIDENCE as more than one mouse had the same problem.