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The intermolecular approach is normally applied to relatively _____ structures.(a) distinctive(b) dissimilar(c) similar(d) differentThe question was posed to me at a job interview.This interesting question is from Protein Structure Comparison in section Structural Bioinformatics of Bioinformatics

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Right answer is (c) similar

Easy explanation: The algorithmic APPROACHES to COMPARING protein geometric properties can be divided into three categories: the FIRST superposes protein structures by MINIMIZING intermolecular distances; the second relies on measuring intramolecular distances of a structure; and the third includes ALGORITHMS that combine both intermolecular and intramolecular approaches.



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