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The phase II reactions are detoxification pathways.(a) True(b) FalseThis question was addressed to me during an online interview.This interesting question is from Drugs Biotransformation topic in chapter Biotransformation of Drugs of Drug Biotechnology

Answer» RIGHT answer is (a) True

The explanation is: In the phase, II reactions tissue reactive and carcinogenic metabolites are RENDERED HARMLESS by conjugation with glutathione. The Phase II reactions terminate the pharmacologic activity of XENOBIOTICS.


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