The scoring scheme based on the combined stabilizing and destabilizing interactions forms the foundation of the ab initio RNA secondary structure prediction method.(a) True(b) FalseI have been asked this question in a national level competition.The above asked question is from RNA Secondary Structure Prediction Methods in chapter RNA Structure Prediction of Bioinformatics

The scoring scheme based on the combined stabilizing and destabilizing

1.	The scoring scheme based on the combined stabilizing and destabilizing interactions forms the foundation of the ab initio RNA secondary structure prediction method.(a) True(b) FalseI have been asked this question in a national level competition.The above asked question is from RNA Secondary Structure Prediction Methods in chapter RNA Structure Prediction of Bioinformatics
Answer» Correct CHOICE is (a) True Explanation: Parameters for calculating different destabilizing energies have also been determined and can be used as penalties for secondary structure CALCULATIONS. This method WORKS by first finding all possible base-pairing patterns from a sequence and then calculating the TOTAL energy of a potential secondary structure by taking into account all the ADJACENT stabilizing and destabilizing forces.

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