There are two chromosomes 1- A—B—C—D—E and 2- F—G—H— I, if A—B—C and F—G undergo reciprocal translocation what will not be true?(a) New sequence at 1 will be C—D—E—F—G(b) The 1 will then pair with both 1’ and 2’(c) Pairing will be between same gene loci only(d) 2nd chromosome will become longerThis question was addressed to me during a job interview.I need to ask this question from Chromosomal Abnormalities : Translocation topic in portion Chromosomal Basis of Inheritance of Cytogenetics

There are two chromosomes 1- A—B—C—D—E and 2- F—G—H— I,

1.	There are two chromosomes 1- A—B—C—D—E and 2- F—G—H— I, if A—B—C and F—G undergo reciprocal translocation what will not be true?(a) New sequence at 1 will be C—D—E—F—G(b) The 1 will then pair with both 1’ and 2’(c) Pairing will be between same gene loci only(d) 2nd chromosome will become longerThis question was addressed to me during a job interview.I need to ask this question from Chromosomal Abnormalities : Translocation topic in portion Chromosomal Basis of Inheritance of Cytogenetics
Answer» The CORRECT OPTION is (a) New sequence at 1 will be C—D—E—F—G The best explanation: In reciprocal TRANSLOCATION, the PARTS are EXCHANGED between two chromosomes in same position. So, the new sequence of 1 should be F—G—C—D—E.

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