Transposition doesn’t require much sequence homology between two genetic molecules, based on this hey can help in _____________(a) Homologous DSB repair(b) Non-homologous end joining(c) Site-specific recombination(d) Homologous recombinationThe question was posed to me during an interview for a job.This intriguing question comes from Chromosomal Abnormalities : Translocation in portion Chromosomal Basis of Inheritance of Cytogenetics

Transposition doesn’t require much sequence homology between two gen

1.	Transposition doesn’t require much sequence homology between two genetic molecules, based on this hey can help in _____________(a) Homologous DSB repair(b) Non-homologous end joining(c) Site-specific recombination(d) Homologous recombinationThe question was posed to me during an interview for a job.This intriguing question comes from Chromosomal Abnormalities : Translocation in portion Chromosomal Basis of Inheritance of Cytogenetics
Answer» Correct answer is (c) Site-specific RECOMBINATION To elaborate: In case of site specific recombination there WOULD be very little or no homology between the donor and recipient site, this can be IMPOSED by translocation. Translocation doesn’t play a part in homologous repair or NHEJ.

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