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What are the results of pericentric inversion with single crossing over?(a) Two normal, one dicentric and one acentric chromosome(b) 2 dicentric and 2 acentric chromosomes(c) Four normal chromosomes with centriomere in different positions(d) 3 normal chromosome, one abnormal acentric chromosomeI had been asked this question in an internship interview.My question is from Chromosomal Abnormality : Inversion topic in portion Chromosomal Basis of Inheritance of Cytogenetics

Answer»

The correct option is (a) Two normal, one dicentric and one acentric CHROMOSOME

The EXPLANATION: RECOMBINATION in the paracentric region will take place between only two STRANDS, so the other two strands will be normal. This recombination will RESULT in one dicentric chromosome and another acentric chromosome.



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