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What is the major end product of oxidation of aromatic carbon atoms?(a) Arenols(b) Catechol(c) Glutathione(d) Arene oxideThis question was posed to me during an interview.My doubt is from Drugs Biotransformation in division Biotransformation of Drugs of Drug Biotechnology

Answer»

The correct choice is (a) Arenols

The best explanation: The oxidation of aromatic CARBON ATOMS proceeds via formation of a reactive intermediate ARENE OXIDE. This arene oxide in most cases is converted into arenols and in some cases produces minor products such as catechols and glutathione conjugates.



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