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What is the name of the process where structurally different compounds interact with the enzyme and prevent the metabolism of the drug?(a) Altered physiology(b) Repression(c) Non-competitive inhibition(d) Competitive inhibitionI had been asked this question in an interview for job.This question is from Drugs Biotransformation topic in chapter Biotransformation of Drugs of Drug Biotechnology

Answer»

The correct option is (c) Non-competitive INHIBITION

To explain I WOULD SAY: Non-competitive inhibition happens when structurally different compounds interact with the enzyme and PREVENT the metabolism of the drug. This interaction is not structured SPECIFICALLY. So lead, mercury, arsenic, organophosphorus insecticides inhibit enzymes noncompetitively.



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