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What provides the atom of oxygen for the making of water?(a) From the cytochrome 450(b) From the environment(c) From the activated oxygen P-450 substrate complex(d) From cytochrome reductaseI got this question during an interview.My doubt is from Drugs Biotransformation topic in division Biotransformation of Drugs of Drug Biotechnology

Answer»

Right choice is (C) From the activated oxygen P-450 substrate COMPLEX

The best EXPLANATION: One atom of oxygen from the activated oxygen P450 complex is transferred to the substrate to yield the oxidized product and the other atom forms water. The free oxidized FORM of cytochrome P-450 is ready to attach to another MOLECULE of substrate.



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