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Which enzyme is of the utmost importance for the 2nd step in the formation of Glucuronide?(a) Esterase(b) Amidases(c) Transferase(d) UDP-glucuronyl transferaseThe question was asked in an online interview.The origin of the question is Drugs Biotransformation topic in chapter Biotransformation of Drugs of Drug Biotechnology |
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Answer» RIGHT choice is (d) UDP-glucuronyl transferase The explanation is: The moieties transferred to the substrates in a phase II reactions possess characteristics that are, simple endogenous molecules, large groups, and STRONG nonpolar or IONIC groups are attached to make the substrate WATER soluble. |
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