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Which enzyme is of the utmost importance for the 2nd step in the formation of Glucuronide?(a) Esterase(b) Amidases(c) Transferase(d) UDP-glucuronyl transferaseThe question was asked in an online interview.The origin of the question is Drugs Biotransformation topic in chapter Biotransformation of Drugs of Drug Biotechnology

Answer» RIGHT choice is (d) UDP-glucuronyl transferase

The explanation is: The moieties transferred to the substrates in a phase II reactions possess characteristics that are, simple endogenous molecules, large groups, and STRONG nonpolar or IONIC groups are attached to make the substrate WATER soluble.


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