Which of the following drugs are ulcer protectives?(a) Cimetidine(b) Omeprazole(c) Sucralfate(d) MisoprostolI have been asked this question in an internship interview.The above asked question is from Pharmacotherapy of Peptic Ulcer in section Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology

Which of the following drugs are ulcer protectives?(a) Cimetidine(b) O

1.	Which of the following drugs are ulcer protectives?(a) Cimetidine(b) Omeprazole(c) Sucralfate(d) MisoprostolI have been asked this question in an internship interview.The above asked question is from Pharmacotherapy of Peptic Ulcer in section Histamine, Bradykinin and their Antagonists, Pharmacotherapy of Gastric Ulcer, Peptic Ulcer of Drug Biotechnology
Answer» Right OPTION is (c) Sucralfate The best explanation: Ulcer protectives are such as sucralfate, Colloidal Bismuth Subricate. These drugs have the TENDENCY to bind to damaged proteins. Thus they binds to the corroded area of the stomach forms a layer and HELPS preventing further damage. Neutralization of gastric ACID by antacids are by sodium carbonate, MAGNESIUM hydroxide, etc.

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